Drugs and Supplements

Over the Counter (OTC)

Loratadine/Pseudoephedrine

Loratadine/Pseudoephedrine

lor-AT-a-deen

soo-doe-e-FED-rin SUL-fate

Indications for Use

Treats hay fever symptoms such as a runny or stuffy nose, sneezing, and watery eyes. Loratadine is an antihistamine, and pseudoephedrine is a decongestant.

Brand Name(s)

  • Claritin-D
  • Alavert D-12 Hour
  • Leader Allergy Relief D-12
  • The Medicine Shoppe Allergy Relief D12
  • Claritin-D 12HR
  • Loratadine-D
  • Good Neighbor Allergy & Congestion Relief 24 Hour
  • Leader Allergy Relief D-24
  • Clear-Atadine D
  • Claritin-D 24 Hour
  • Quality Choice Loratadine-D
  • There may be other brand names for this medicine.

    When You Should Not Take the Medication

    You should not use this medicine if you have had an allergic reaction to loratadine or pseudoephedrine. If you have glaucoma, problems urinating, severe high blood pressure, or heart disease or if you have taken a type of medicine called an MAO inhibitor (such as Marplan®, Parnate®, or Nardil®) in the past 14 days, then you should not take this medicine.

    How to Use this Medicine

    12 Hour Tablet, Long Acting Tablet, 24 Hour Tablet

    Your doctor will tell you how much to take and how often. You should not use more of this medicine than your doctor ordered.

    Claritin-D 24 Hour® extended-release tablets should only be taken once a day.

    Take the tablet with a full glass of water.

    Swallow the tablet whole. Do not break, crush, or chew.

    It is best to take this medicine on an empty stomach.

    Drink plenty of liquids while taking this medicine.

    If a Dose is Missed


    Take your medicine as soon as possible unless it is almost time for your next dose. If you are taking Claritin-D 24 Hour®, you should only take one dose a day.

    Skip the missed dose if it is almost time for your next regular dose.

    You should not use two doses at the same time.

    How to Store and Dispose of this Medicine


    Keep the medicine at room temperature in a closed container, away from heat, moisture, and direct light.

    Keep all medicine out of the reach of children.

    Drugs and Foods to Avoid

    Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

    Avoid drinking alcohol while taking this medicine.

    You should not use other antihistamines or decongestants while taking this medicine, including those you buy without a doctor's prescription.

    Make sure your doctor knows if you are also taking medicine for high blood pressure, ketoconazole (Nizoral®), cimetidine (Tagamet®), or erythromycin (E.E.S.®, ERYC®, Ery-Tab®, and others).

    Warnings While Using this Medicine


    You should not use Claritin-D 24 Hour® tablets if you have trouble swallowing tablets. The tablet could get stuck as it passes down toward your stomach.

    If you are pregnant or breastfeeding, talk to your doctor before taking this medicine.

    Make sure your doctor knows if you have liver disease, diabetes, thyroid problems, high blood pressure, kidney disease, or prostate problems before taking this medicine.

    This medicine may make you drowsy or dizzy. Be careful if you are driving or using machinery.

    Possible Side Effects While Using this Medicine


    Call your doctor right away if you notice any of these side effects:
    Wheezing or trouble breathing
    Fast, pounding, or irregular heartbeat
    Fainting or passing out

    If you notice these less serious side effects, talk with your doctor:
    Trouble sleeping
    Headache
    Nervousness
    Dry mouth or nose
    Dizziness or drowsiness

    If you notice other side effects that you think are caused by this medicine, tell your doctor.