Drugs and Supplements

Prescription Drugs

WelChol, Colesevelam, side effects, drug interactions, overdose, dosage
Brand name:

WelChol

Generic name: Colesevelam


Why is WelChol prescribed?

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WelChol is used to lower blood cholesterol levels when diet and exercise prove insufficient. It works by binding with cholesterol-based bile acids to take them out of circulation. This prompts the liver to produce a replacement supply of bile acids, drawing the extra cholesterol it needs out of the bloodstream.


Most important fact about WelChol

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WelChol is usually added to a treatment regimen only when other measures have failed to produce adequate results. Often, diet and exercise are enough to bring cholesterol levels under control. Likewise, it's sometimes sufficient to simply treat an underlying problem such as diabetes, underactive thyroid, kidney disease, a liver disorder, or alcoholism.

Whatever your other treatment measures may be, it's important to remember that WelChol is intended to supplement them, rather than replace them outright. To get the full benefit of the medication, you need to stick to the diet, exercise program, and other treatments your doctor prescribes. All these efforts to keep your cholesterol levels normal are important because together they may lower your risk of heart disease.


How should you take WelChol?

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WelChol should be taken at mealtime with a liquid.

  • If you miss a dose...
    Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never take 2 doses at the same time.
  • Storage instructions...
    Store at room temperature and protect from moisture.

What side effects may occur?

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WelChol is not absorbed by the body, so it is relatively free of side effects. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking WelChol.

  • Side effects may include:
    Constipation, indigestion, muscle aches, sore throat, weakness

Why should WelChol not be prescribed?

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You should not take WelChol if you have a bowel obstruction or the product gives you an allergic reaction.


Special warnings about WelChol

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If you have difficulty swallowing or suffer from severe digestive problems, use WelChol with caution; it hasn't been tested under these conditions. The drug has also not been studied in children.


Possible food and drug interactions when taking WelChol

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If WelChol is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Always check with your doctor before combining WelChol with other medication, especially verapamil.


Special information if you are pregnant or breastfeeding

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There is no evidence that this drug causes harm during pregnancy. Nevertheless, be sure to let the doctor know if you are pregnant, plan to become pregnant, or are breastfeeding. There is a possibility that WelChol could interfere with the absorption of needed vitamins.


Recommended dosage for WelChol

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ADULTS


The usual dosage is 6 tablets a day, taken as a single dose or divided into 2 doses. If you're taking WelChol with one of the cholesterol-lowering statin drugs, the maximum recommended daily dosage is 6 tablets. If you're taking WelChol alone, the maximum is 7.


Overdosage

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Since WelChol is not absorbed by the body, the chances of serious toxicity are low. Still, if you suspect an overdose, call your doctor immediately.