AcipHex
Generic Name: Rabeprazole
What is AcipHex?
Aciphex is a medicine that blocks the production of stomach acid. It belongs to a class of drugs known as proton pump inhibitors (PPIs). Aciphex is used for the treatment of gastroesophageal reflux disease (GERD) and ulcers; for long-term treatment of certain conditions marked by excessive acid production, such as Zollinger-Ellison syndrome; and as part of a combination treatment to eliminate the bacteria that often causes ulcers (known as H. pylori).What is the most important information I should know about AcipHex?
Taking Aciphex may hide the symptoms of serious stomach problems. Symptom relief does not rule out the existence of other serious conditions, including cancer.Who should not take AcipHex?
Do not take Aciphex if you are allergic to any of its ingredients or to any other PPI.What should I tell my doctor before I take the first dose of AcipHex?
Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Aciphex. Also, talk to your doctor about your complete medical history, especially if you have any allergies or liver problems. Inform your doctor if you are pregnant, planning to become pregnant, or are breastfeeding.What is the usual dosage?
The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.Gastroesophageal Reflux Disease (GERD)
Adults: The recommended dose is a 20 milligram (mg) tablet once a day for 4-8 weeks. Depending on your response, your doctor may suggest another 8 weeks of treatment.
Adolescents ≥12 years: The recommended dose is 20 mg once a day for up to 8 weeks.
Prevention of Duodenal Ulcer Due to H. pylori Infection
Adults: This treatment involves taking three different medications. The usual dose for the triple therapy is: Aciphex 20 mg twice a day for 7 days; amoxicillin 1,000 mg twice a day for 7 days; and clarithromycin 500 mg twice a day for 7 days.
Treatment of Duodenal Ulcers
Adults: The recommended dose is one 20 mg tablet once a day after the morning meal for up to 4 weeks.
Treatment of Excess Stomach Acid (such as Zollinger-Ellison Syndrome)
Adults: The recommended dose is 60 mg once a day. However, treatment varies depending on the particular condition.
How should I take AcipHex?
Aciphex is usually taken once a day, with or without food. Your doctor will tell you whether you should take Aciphex after a meal based on your medical condition. Swallow the tablets whole.What should I avoid while taking AcipHex?
Do not chew, crush, or split the tablets, since this will damage them and the medicine will not work. Tell your doctor if you cannot swallow tablets whole.What are possible food and drug interactions associated with AcipHex?
If Aciphex is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Aciphex with the following: atazanavir, cyclosporine, digoxin, ketoconazole, warfarin, and antibiotics.What are the possible side effects of AcipHex?
Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.Side effects may include: allergic reactions, bone pain, chest pain, chills, constipation, diarrhea, dry mouth, fever, gas, leg cramps, light sensitivity, migraines, nausea, sore throat, upset stomach, vomiting
Can I receive AcipHex if I am pregnant or breastfeeding?
The effects of Aciphex during pregnancy and breastfeeding are unknown. Talk with your doctor before taking this drug if you are pregnant, plan to become pregnant, or are breastfeeding.What should I do if I miss a dose of AcipHex?
Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take two doses at once.How should I store AcipHex?
Store at room temperature, away from moisture.
I'm Kristen Dore, PharmD. Welcome to PDR Health!
