Adcetris

Generic Name: Brentuximab Vedotin

  • What is Adcetris?

    Adcetris is a medicine used to treat a type of cancer called Hodgkin's lymphoma after failure of stem cell transplant or at least two prior cancer treatment regimens. It is also used to treat a type of cancer called systemic anaplastic large cell lymphoma after failure of at least one prior cancer treatment regimen. Adcetris blocks cell growth, especially in cells that grow fast, such as cancer cells. Adcetris is administered intravenously (through a vein in your arm).

  • What is the most important information I should know about Adcetris?

    Adcetris can cause peripheral neuropathy, which is a nerve disorder. Tell your doctor immediately if you experience numbness, tingling of your hands or feet, burning sensation, pain, or muscle weakness. Your doctor will monitor you for neuropathy and may adjust your dose.

    An infusion reaction or anaphylaxis (a serious and rapid allergic reaction that may result in death if not immediately treated) can occur while infusing Adcetris. Tell your doctor immediately if you experience a fever, chills, rash, or breathing problems. Also, tell your doctor if you have experienced this reaction before while receiving Adcetris.

    Adcetris can cause a decrease in neutrophil counts in your blood (a type of cell needed to fight infections). This may increase your risk of developing an infection. Your doctor will monitor your complete blood counts and will adjust your dose depending on the results if needed. Tell your doctor if you experience a fever, chills, cough, pain on urination, or other signs of an infection.

    Adcetris can cause serious skin reactions. Tell your doctor immediately if you experience a severe or worsening rash or itching.

    Adcetris can harm your unborn or newborn baby if you take it during pregnancy or breastfeeding. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • Who should not take Adcetris?

    Your doctor will not administer Adcetris to you if you are allergic to it or any of its ingredients.

  • What should I tell my doctor before I take the first dose of Adcetris?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Adcetris. Also, talk to your doctor about your complete medical history, especially if you have a history of peripheral neuropathy or low neutrophil counts, or are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: Your doctor will administer the appropriate dose for you based on your body weight and condition.

    If you have peripheral neuropathy or low neutrophil counts, your doctor will adjust your dose appropriately.

  • How should I take Adcetris?

    Your doctor will administer Adcetris to you.

  • What should I avoid while taking Adcetris?

    Do not miss your scheduled follow-up appointments with your doctor.

  • What are possible food and drug interactions associated with Adcetris?

    If Adcetris is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to tell your doctor if you are taking any of the following prior treatment with Adcetris: ketoconazole or rifampin.

  • What are the possible side effects of Adcetris?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: abdominal pain, cough, diarrhea, fever, nausea, pain, peripheral neuropathy, rash, tiredness, upper respiratory tract infection, vomiting

  • Can I receive Adcetris if I am pregnant or breastfeeding?

    Adcetris can harm your unborn or newborn baby if you take it during pregnancy or breastfeeding. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Adcetris?

    Adcetris should be given under special circumstances determined by your doctor. If you miss your scheduled dose, contact your doctor.

  • How should I store Adcetris?

    Your doctor will store this medication for you.