What is Adcirca?Adcirca is a medicine used to treat pulmonary arterial hypertension (high blood pressure in your lungs) to help improve your ability to exercise.
What is the most important information I should know about Adcirca?You should never take Adcirca if you are taking medicines that contain nitrates (often used for chest pain; or nitroglycerin in any form, including tablets, patches, sprays, or ointments). If you take Adcirca with any nitrate medicine, your blood pressure could suddenly drop to an unsafe or life-threatening level, or you could get dizzy, faint, and even have a heart attack or stroke.
Adcirca can cause decreased eyesight or loss of vision in your eyes. If you notice a sudden decrease or loss of vision in your eyes, call your doctor immediately.
Adcirca can cause a sudden decrease or loss of hearing, sometimes with ringing in your ears and dizziness. If you notice a sudden decrease or loss of your hearing, call your doctor immediately.
In men, an erection that lasts more than 4 hours (with or without pain) may occur. If you have an erection that lasts more than 4 hours, you must be treated as soon as possible as you can have lasting damage to your penis, including the ability to have erections.
Who should not take Adcirca?Do not take Adcirca if you are allergic to it or any of its ingredients. Also, do not take Adcirca if you are taking medicines called nitrates or are using recreational drugs called "poppers" (such as amyl nitrate, butyl nitrate, or nitrite).
What should I tell my doctor before I take the first dose of Adcirca?Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Adcirca. Also, talk to your doctor about your complete medical history, especially if you have blockage in the veins of your lungs known as pulmonary veno-occlusive disease, chest pain, heart failure (a condition in which the heart cannot pump enough blood throughout the body), irregular heartbeat, or have had a heart attack, low or uncontrolled high blood pressure; had a stroke; liver problems; kidney problems or you are on dialysis; stomach ulcers; retinitis pigmentosa (a rare genetic eye disease); any sudden vision loss, including any damage to your optic nerve; hearing problems; dizziness; if you have a deformed penis shape, or Peyronie's disease (a disorder affecting the penis), or had an erection that lasted more than 4 hours; have blood cell problems (such as sickle cell anemia, multiple myeloma, or leukemia); are pregnant or plan to become pregnant.
What is the usual dosage?The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.
Adults: The usual recommended dose is 40 milligrams (mg) (two 20-mg tablets) once a day.
If you have kidney impairment or if you require treatment with both Adcirca and ritonavir, your doctor will adjust the dose appropriately.
How should I take Adcirca?Take Adcirca exactly as prescribed by your doctor.
You should take both tablets at the same time, one after the other, every day. You can take Adcirca with or without food. Do not split your dose.
What should I avoid while taking Adcirca?Do not drink more than 4 alcohol-containing drinks in a short period of time while you are taking Adcirca.
Do not take both Adcirca and Cialis (used for the treatment of impotence). In addition, do not take Adcirca and other medicines or treatments for impotence.
What are possible food and drug interactions associated with Adcirca?If Adcirca is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Adcirca with the following: alpha blockers (used to treat prostate disease and high blood pressure), anti-HIV medications (such as ritonavir), bosentan, carbamazepine, certain antibiotics, ketoconazole and itraconazole, medicines used to treat high blood pressure, phenobarbital, or phenytoin.
What are the possible side effects of Adcirca?Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.
Side effects may include: getting red or hot in the face (flushing); headache; muscle pain; nausea; pain in the arms, legs, or back; stomach upset; stuffy or congested nose
Can I receive Adcirca if I am pregnant or breastfeeding?The effects of Adcirca during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
What should I do if I miss a dose of Adcirca?If you miss a dose of Adcirca, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.
How should I store Adcirca?Store at room temperature.