Ambisome

Generic Name: Amphotericin B Liposome

  • What is Ambisome?

    Ambisome is an antifungal medicine used to treat certain fungal infections of the brain or abdomen, including cryptococcal meningitis (brain or spinal cord inflammation) in HIV patients or visceral leishmaniasis (that affects some of the internal organs such as spleen, liver, or bone marrow), respectively. Ambisome is also used to treat or prevent other fungal infections as determined by your doctor. Ambisome is administered intravenously (through a vein in your arm).

  • What is the most important information I should know about Ambisome?

    Ambisome can cause serious allergic reactions that may result in death if not immediately treated. Tell your doctor immediately if you develop a rash, itching, facial swelling, or low blood pressure.

  • Who should not take Ambisome?

    Your doctor will not administer Ambisome to you if you are allergic to it or any of its ingredients.

  • What should I tell my doctor before I take the first dose of Ambisome?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Ambisome. Also, talk to your doctor about your complete medical history, especially if you have kidney or liver disease.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: Your doctor will administer the appropriate dose for you.

  • How should I take Ambisome?

    Your doctor will administer Ambisome to you as an intravenous infusion.

  • What should I avoid while taking Ambisome?

    Do not miss any scheduled follow-up appointments with your doctor.

  • What are possible food and drug interactions associated with Ambisome?

    If Ambisome is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining with the following: certain antibiotics (such as gentamicin or tobramycin), certain antifungals (such as clotrimazole, ketoconazole, miconazole, or fluconazole), certain cancer medications, corticosteroids (such as prednisone), digoxin, or flucytosine.

  • What are the possible side effects of Ambisome?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: abdominal pain, changes in blood pressure, chills, confusion, diarrhea, headache, increased cough, lung problems, nausea, rash, sleep disturbances, vomiting

  • Can I receive Ambisome if I am pregnant or breastfeeding?

    The effects of Ambisome during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Ambisome?

    Ambisome should be given under special circumstances determined by your doctor.

  • How should I store Ambisome?

    Your doctor will store this medication for you.