Generic Name: Alefacept

  • What is Amevive?

    Amevive is a medicine used to treat moderate to severe long-term plaque psoriasis. It is administered intramuscularly (injected into the muscle).

  • What is the most important information I should know about Amevive?

    Amevive can reduce the activity of your immune system and therefore can increase your risk of cancer or serious infections. Tell your doctor if you have cancer or a history of cancer, or if you have any long-term infection or an infection that you had previously. Your doctor will regularly monitor your white blood cell count and other immune cells.

    Anaphylactic reactions (a serious and rapid allergic reaction that may result in death if not immediately treated) can occur when you receive Amevive. Contact your doctor or get emergency help immediately if you develop a rash, difficulty breathing, or swelling of your mouth or tongue.

    Amevive can cause serious liver injury. Tell your doctor if you experience nausea, loss of appetite, tiredness, vomiting, abdominal pain, jaundice (yellowing of the skin or whites of the eyes), easy bruising, dark urine, or pale stools.

  • Who should not take Amevive?

    Do not take Amevive if you are allergic to it or any of its ingredients, or if you are infected with HIV infection (AIDS).

  • What should I tell my doctor before I take the first dose of Amevive?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Amevive. Also, talk to your doctor about your complete medical history, especially if you have allergies, cancer or a history of cancer, infections, or liver problems.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: The recommended dose is 15 milligrams (mg) given once a week for 12 weeks. After completing this 12-week course of treatment, your doctor will decide if you need an additional course of treatment.

  • How should I take Amevive?

    Your doctor will administer Amevive intramuscularly for you in a hospital or clinic setting.

  • What should I avoid while taking Amevive?

    Do not miss your scheduled follow-up appointments with your doctor.

  • What are possible food and drug interactions associated with Amevive?

    No significant interactions have been reported with Amevive at this time. However, always tell your doctor about any medicines you take, including over-the-counter medications, vitamins, and herbal supplements.

  • What are the possible side effects of Amevive?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: abdominal pain, allergic reactions, chills, cough, dark urine, dizziness, easy bruising, fatigue, infections, injection-site reactions (such as bleeding, inflammation, pain, or swelling), itchiness, jaundice, loss of appetite, muscle pain, nausea, pale stools, sore throat, tiredness, vomiting

  • Can I receive Amevive if I am pregnant or breastfeeding?

    The effects of Amevive during pregnancy and breastfeeding are unknown. Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Amevive?

    Amevive should be given under special circumstances determined by your doctor.

  • How should I store Amevive?

    Your doctor will store this medication for you.