Generic Name: Lubiprostone

  • What is Amitiza?

    Amitiza is used to treat chronic constipation in adults when the cause is unknown. It is also used to treat irritable bowel syndrome with constipation in women 18 years and older.
  • What is the most important information I should know about Amitiza?

    People taking Amitiza may experience difficulty breathing or shortness of breath within an hour of the first dose. However, this symptom generally resolves within 3 hours but may recur with repeated dosing.
  • Who should not take Amitiza?

    You should not take Amitiza if you are allergic to any of its ingredients. Also avoid this drug if you have severe diarrhea or a suspected gastrointestinal obstruction.
  • What should I tell my doctor before I take the first dose of Amitiza?

    Before you start Amitiza, tell your doctor about all prescription, over-the-counter, and herbal medication you are taking. Also talk to your doctor about your complete medical history, especially if you have symptoms of a gastrointestinal obstruction or if you are pregnant, plan to become pregnant, or are breastfeeding.
  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Chronic Constipation

    Adults: The usual dose is 24 micrograms (mcg) taken twice daily.

    Irritable Bowel Syndrome with Constipation

    Women 18 years and older: The usual dose is 8 mcg taken twice daily.

  • How should I take Amitiza?

    Take Amitiza as directed by your doctor. Take it with food and water.
  • What should I avoid while taking Amitiza?

    To reduce symptoms of nausea, avoid taking Amitiza on an empty stomach. Report symptoms of severe nausea or diarrhea to your doctor.
  • What are possible food and drug interactions associated with Amitiza?

    If Amitiza is used with certain other drugs, the effects of either could be increased, decreased, or altered. Always check with your doctor before combining Amitiza with any other medication.
  • What are the possible side effects of Amitiza?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: nausea, diarrhea, headache, abdominal pain, gas

  • Can I receive Amitiza if I am pregnant or breastfeeding?

    The effects of taking Amitiza during pregnancy or breastfeeding are unknown. Talk to your doctor if you are pregnant, plan to become, or are breastfeeding.
  • How should I store Amitiza?

    Store at room temperature. Protect from extreme temperatures.