Amphotericin B

Generic Name: Amphotericin B

  • What is Amphotericin B?

    Amphotericin B is an antifungal medicine used to treat certain life-threatening fungal infections, including Candida infections. Amphotericin B is administered intravenously (through a vein in your arm).

  • What is the most important information I should know about Amphotericin B?

    Amphotericin B can cause reactions, such as fever, shaking, chills, low blood pressure, loss of appetite, nausea, vomiting, headache, and rapid breathing. These reactions are usually more common during the first 1-3 hours after starting the infusion and usually diminish with the following doses.

    Amphotericin B can cause lung or kidney problems. Your doctor will monitor your lung and kidney function during administration of amphotericin B.

  • Who should not take Amphotericin B?

    Your doctor will not administer amphotericin B if you are allergic to it or any of its ingredients, unless your doctor decides the condition is life-threatening and requires treatment.

  • What should I tell my doctor before I take the first dose of Amphotericin B?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with amphotericin B. Also, talk to your doctor about your complete medical history, especially if you have kidney or liver disease, or lung problems.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: Your doctor will administer the appropriate dose for you.

  • How should I take Amphotericin B?

    Your doctor will administer amphotericin B to you as an intravenous infusion.

  • What should I avoid while taking Amphotericin B?

    Do not miss any scheduled follow-up appointments with your doctor.

  • What are possible food and drug interactions associated with Amphotericin B?

    If amphotericin B is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining amphotericin B with the following: certain antibiotics (such as gentamicin or tobramycin), certain antifungals (such as clotrimazole, ketoconazole, miconazole, or fluconazole), certain cancer medications, corticosteroids (such as prednisone), digoxin, or flucytosine.

  • What are the possible side effects of Amphotericin B?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: diarrhea, fever, headache, indigestion, injection-site pain, joint or muscle pain, loss of appetite, low blood pressure, nausea, rapid breathing, stomach pain, vomiting, weakness, weight loss

  • Can I receive Amphotericin B if I am pregnant or breastfeeding?

    The effects of amphotericin B during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Amphotericin B?

    Amphotericin B should be given under special circumstances determined by your doctor.

  • How should I store Amphotericin B?

    Your doctor will store this medication for you.