Generic Name: Amlodipine

  • What is this medication and its most common uses?

    Amturnide is a medicine used to treat high blood pressure. Amturnide contains three medicines that work in different ways to reduce your blood pressure: aliskiren, amlodipine, and hydrochlorothiazide.

  • What should I know when beginning and continuing on this medication?

    How does this medication work?

    Aliskiren and amlodipine work by blocking substances in your body that cause blood vessels to narrow. By blocking these substances, aliskiren and amlodipine relax and widen your blood vessels, allowing your blood to flow through with less resistance. Hydrochlorothiazide works by eliminating extra fluid and sodium (salt) from your body. This helps to lower your blood pressure.

    What are the beneficial effects of this medication and when should I begin to have results?

    What: By lowering your blood pressure, Amturnide may lower your risk of a stroke or a heart attack. Also, it is taken just once a day, which may make it easier for you to remember.

    When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's instructions. Though you may not feel an improvement or change in the way you feel, it is very important to keep taking your medicine as prescribed to keep your condition under control.

    How do I know it is working?

    Check your blood pressure regularly. Your healthcare provider may also check your blood pressure at every visit. Following an appropriate diet and exercise plan will also affect your blood pressure results.

  • What are the possible side effects of this medication?

    The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

    Amturnide can harm your unborn baby. Talk to your healthcare provider about other ways to lower your blood pressure if you plan to become pregnant. Tell your healthcare provider right away if you become pregnant while taking Amturnide.

    More common side effects may include: swelling of your legs, ankles, or hands; dizziness; headache; runny or stuffy nose.

    Less common side effects may include:

    Serious allergic reactions with symptoms such as extreme swelling of your face, lips, or tongue; difficulty breathing or swallowing; chest tightness; hives; rash; swelling; itching; dizziness; vomiting; or abdominal (stomach area) pain.

    Low blood pressure with symptoms such as lightheadedness, especially during the first few days of treatment with Amturnide. Dehydration, excessive sweating, diarrhea, or vomiting can lead to an excessive fall in your blood pressure, which can cause lightheadedness and possible fainting.

    Possible increased chest pain or risk of a heart attack.

    Kidney problems with symptoms such as swelling in your feet, ankles, or hands; or unexplained weight gain.

    Changes in electrolytes (chemicals that are important for the cells in your body to function, such as sodium and potassium) with symptoms such as dry mouth, thirst, weakness, tiredness, drowsiness, restlessness, muscle pains or cramps, muscle tiredness, dizziness or fainting, low or no urine output, fast heartbeat, or nausea and vomiting.

    Temporary nearsightedness (trouble seeing objects farther away) or glaucoma (high pressure in the eye) with symptoms such as changes in your vision or eye pain that may occur within hours to weeks of starting Amturnide.

  • Who should not take this medication?

    Do not take Amturnide if you are allergic to it, any of its ingredients, or other sulfonamide-derived medications (such as sulfamethoxazole).

    Do not take Amturnide if you are unable to produce urine.

    Do not take Amturnide if you have diabetes and are taking another blood pressure/heart medicine called an angiotensin receptor blocker (ARB) (such as losartan or valsartan) or an angiotensin-converting enzyme (ACE) inhibitor (such as captopril or lisinopril).

  • What should I tell my healthcare provider before I take the first dose of this medication?

    Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Amturnide. Also, talk to your healthcare provider about your complete medical history, especially if you have diabetes; kidney, heart, or liver problems; recently had a heart attack; have lupus (a disease that affects the immune system); had an allergic reaction to another blood pressure medicine; or if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

    Adults: Your healthcare provider will prescribe the appropriate dose for you based on your previous blood pressure medication, and may increase your dose as needed, until the desired effect is achieved.

    If you have kidney or liver impairment, your healthcare provider will adjust your dose appropriately.

  • How should I take this medication?

    Take Amturnide exactly as prescribed by your healthcare provider. Do not change your dose or stop taking Amturnide without first taking to your healthcare provider.

    Take Amturnide once a day, with or without food.

    If you take a cholesterol-lowering medicine called colesevelam, take Amturnide at least 4 hours before you take this medicine.

  • What should I avoid while taking this medication?

    Do not become pregnant while taking this medication.

    Do not drink alcohol while you are taking Amturnide.

    Do not take potassium supplements or salt substitutes that contain potassium without first talking to your healthcare provider.

  • What are the possible food and drug interactions associated with this medication?

    If Amturnide is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Amturnide with the following: alcohol, ACE inhibitors (such as enalapril or lisinopril), cholestyramine, colestipol, cyclosporine, diabetes medicines (such as insulin or glyburide), itraconazole, lithium, nonsteroidal anti-inflammatory drugs (NSAIDs) (such as ibuprofen or naproxen), potassium supplements, salt substitutes containing potassium, or simvastatin.

  • May I receive this medication if I am pregnant or breastfeeding?

    Do not take Amturnide if you are pregnant or breastfeeding. Amturnide may harm your unborn baby. Amturnide can be found in your breast milk if you take it while breastfeeding. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of this medication?

    If you miss a dose of Amturnide, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store this medication?

    Store at room temperature. Protect from heat and moisture.