Apidra
Generic Name: Insulin Glulisine, rDNA
What is Apidra?
Apidra is a rapid-acting insulin used to control high blood sugar in adults and children with diabetes.What is the most important information I should know about Apidra?
Do not change your insulin without talking to your doctor. You must test your blood sugar levels while using Apidra. Your doctor will tell you how often you should test your blood sugar and what to do if the levels are high or low. Do not mix Apidra with another insulin or liquid when using a pump.Do not take Apidra if your blood sugar is low. Be aware of symptoms of low blood sugar.
Apidra may lower your potassium levels and should therefore be monitored.
Your blood sugar and insulin dose may need to be closely monitored if you have kidney or liver impairment.
Who should not take Apidra?
Do not take Apidra if you are allergic to insulin glulisine or any of its other ingredients. Talk with your doctor about your allergies to avoid a reaction.Do not take Apidra if you have low blood sugar.
What should I tell my doctor before I take the first dose of Apidra?
Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Apidra. Also, talk to your doctor about your complete medical history, especially if you have kidney or liver problems.What is the usual dosage?
The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.Adults and children ≥4 years: Apidra should be injected 15 minutes before a meal or 20 minutes after starting a meal. Your doctor will prescribe the appropriate dose for you.
How should I take Apidra?
Inject Apidra under the skin of your upper arm, stomach area, or thigh; never inject it into a vein or muscle. If you use a pump, infuse Apidra through the skin of your stomach; do not mix it with any other insulin or liquid. Alternate injection sites within the same body area. The Apidra in the pump reservoir should be changed every 48 hours. Only use Apidra that is clear and colorless.What should I avoid while taking Apidra?
Avoid alcohol while taking Apidra.Avoid operating heavy machinery if you experience low blood sugar while taking Apidra.
What are possible food and drug interactions associated with Apidra?
If Apidra is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Apidra with the following: ACE inhibitors, alcohol, atypical antipsychotics, beta-blockers, clonidine, corticosteroids, danazol, disopyramide, diuretics, estrogens, fibrates, fluoxetine, glucagon, guanethidine, isoniazid, lithium salts, monoamine oxidase inhibitors, pentamidine, pentoxifylline, phenothiazine derivatives, proestrogens, propoxyphene, protease inhibitors, reserpine, salicylates, somatostatin analogs, somatropin, sulfonamide antibiotics, albuterol, epinephrine, terbutaline, or thyroid hormones.What are the possible side effects of Apidra?
Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.Side effects may include: hypoglycemia (low blood sugar), hyperglycemia (high blood sugar), allergy, skin reactions, injection site reactions, weight gain
Symptoms of low blood sugar may include: anxiety; irritability; tingling in your hands, feet, lips, or tongue; dizziness, lightheadedness, or drowsiness; headache; blurred vision; fast heartbeat; sweating; shaking
Symptoms of high blood sugar may include: confusion or drowsiness, thirst, decreased appetite, nausea, vomiting, fast heartbeat, increased urination
Can I receive Apidra if I am pregnant or breastfeeding?
The effects of Apidra on pregnancy and nursing are unknown. If you are pregnant, plan to become pregnant, or are breastfeeding, talk with your doctor.What should I do if I miss a dose of Apidra?
Ask your doctor for specific instructions to follow in case you ever miss a dose of Apidra.How should I store Apidra?
Store unopened vials and pens in a refrigerator, out of direct heat and sunlight. Once a vial or pen is opened and in use, it can be stored at or below room temperature for up to 28 days.
I'm Beth Isaac, PharmD. Welcome to PDR Health!
