What is Aredia?Aredia is a medicine used to treat Paget's disease (a painful condition that weakens and deforms the bones) and high blood calcium levels due to cancer. It is also used with other anticancer medications to treat bone complications due to multiple myeloma (a type of cancer that affects white blood cells) and cancer that spread to the bone due to breast cancer. Aredia is administered intravenously (through a vein in your arm).
What is the most important information I should know about Aredia?Aredia can cause kidney problems that can lead to kidney failure. Your doctor will monitor your kidney function while you are receiving Aredia.
Aredia can cause osteonecrosis (jaw-bone problems). Your doctor should examine your mouth before you start Aredia. Tell your doctor if you feel pain, swelling, or numbness in your jaw; or if you have any signs of muscular or skeletal pain. Maintain good oral hygiene and complete a dental exam with preventive tooth and gum care before receiving Aredia.
Who should not take Aredia?Your doctor will not administer Aredia to you if you are allergic to it or any of its ingredients, or if you are pregnant.
What should I tell my doctor before I take the first dose of Aredia?Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Aredia. Also, talk to your doctor about your complete medical history, especially if you have kidney, jaw, or dental problems; or low calcium, phosphate, or magnesium levels in your blood. Also, tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding.
What is the usual dosage?The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.
Adults: Your doctor will administer the appropriate dose for you intravenously, based on your condition.
How should I take Aredia?Your doctor will administer Aredia to you.
What should I avoid while taking Aredia?Do not miss your follow-up appointments with your doctor.
What are possible food and drug interactions associated with Aredia?If Aredia is used with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Aredia with thalidomide.
What are the possible side effects of Aredia?Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.
Side effects may include: abdominal pain; anemia; bone pain; constipation; high blood pressure; loss of appetite; low blood magnesium, phosphate, or potassium levels; nausea; pain; swelling; urinary tract infections; vomiting
Can I receive Aredia if I am pregnant or breastfeeding?Your doctor will not administer Aredia to you if you are pregnant. The effects of Aredia during breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
What should I do if I miss a dose of Aredia?Aredia should be given under special circumstances determined by your doctor.
How should I store Aredia?Your doctor will store this medication for you.