Arixtra

Generic Name: Fondaparinux

  • What is Arixtra?

    Arixtra is a blood thinning medicine used subcutaneously (just below the skin) to help prevent blood clots from forming in people who have had certain surgeries of the hip, knee, or the stomach area. It is also used to treat people who have blood clots in their legs or blood clots that travel to the lungs.

  • What is the most important information I should know about Arixtra?

    Arixtra can cause severe bleeding. In addition, you may bruise or bleed more easily while you are receiving Arixtra, and it may take longer than usual for bleeding to stop. Tell your doctor immediately if you have any bleeding, bruising, rash, or dark red spots under the skin.

    Certain kidney problems can increase your risk of bleeding with Arixtra. Your doctor may check your kidney function while you are using Arixtra.

    Arixtra can cause thrombocytopenia (low blood platelet [type of blood cells that form clots to help stop bleeding] counts), anemia (low red blood cell counts), and increased liver enzymes. Your doctor may check your platelet and red blood cell counts as well as your liver function while you are receiving Arixtra.

  • Who should not take Arixtra?

    Your doctor will not administer Arixtra to you if you are allergic to it or any of its ingredients (such as latex), or if you have severe kidney impairment, a bacterial infection in your heart, thrombocytopenia, if you weigh less than 110 pounds (if you are using Arixtra to prevent blood clots after surgery), or if you are bleeding.

  • What should I tell my doctor before I take the first dose of Arixtra?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Arixtra. Also, talk to your doctor about your complete medical history, especially if you have kidney problems, any bleeding disorder (such as stomach ulcers), had recent surgery (including eye surgery), have had a stroke, diabetic eye disease, high blood pressure, latex allergy, or are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: Your doctor will prescribe the appropriate dose for you, based on your condition and body weight.

  • How should I take Arixtra?

    Use Arixtra exactly as prescribed by your doctor. If your doctor tells you to give yourself injections at home, you will be shown how to give the injections before you inject them on your own.

    Do not use Arixtra if the solution appears discolored (solution should normally appear clear), you see any particles in the solution, or the syringe is damaged.

  • What should I avoid while taking Arixtra?

    Do not miss your scheduled follow-up appointments with your doctor.

  • What are possible food and drug interactions associated with Arixtra?

    If Arixtra is administered with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Arixtra with the following: aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs) (such as ibuprofen or naproxen), or other blood thinners (such as clopidogrel or warfarin).

  • What are the possible side effects of Arixtra?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: allergic reactions, anemia, bleeding, confusion, dizziness, insomnia (sleeping problems), itching, low blood pressure, low potassium levels, pain at the injection site, purple or red discoloration of your skin, rash

  • Can I receive Arixtra if I am pregnant or breastfeeding?

    The effects of Arixtra during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Arixtra?

    If you miss a dose of Arixtra, inject it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not inject two doses at once.

  • How should I store Arixtra?

    Your doctor will store this medication for you.