Aromasin

Generic Name: Exemestane

  • What is Aromasin?

    Aromasin is used to treat advanced breast cancer in postmenopausal women whose disease has gotten worse after treatment with tamoxifen. Aromasin is used to reduce the risk of breast cancer recurrence in postmenopausal women with estrogen receptor positive early stage breast cancer who have received two to three years of tamoxifen and switch to Aromasin to complete a total of five consecutive years of therapy.
  • What is the most important information I should know about Aromasin?

    Aromasin may reduce your bone mineral density over time.
  • Who should not take Aromasin?

    Do not take Aromasin if you have not gone through menopause, are taking hormone replacement therapy (HRT), are on medications that contain estrogen, or if you have an allergy to Aromasin or its inactive ingredients.
  • What should I tell my doctor before I take the first dose of Aromasin?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Aromasin. Also, talk to your doctor about your complete medical history, especially if you have kidney or liver disease.
  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: The recommended dose of Aromasin in early and advanced breast cancer is one 25-mg tablet once daily.

    For patients receiving Aromasin with a potent CYP 3A4 such as rifampicin or phenytoin, the recommended dose of Aromasin is 50 mg once daily.

  • How should I take Aromasin?

    Aromasin should be taken after a meal with plenty of fluids.

    In postmenopausal women with early breast cancer who have been treated with 2-3 years of tamoxifen, treatment with Aromasin should continue in the absence of recurrence or contralateral breast cancer until completion of five years of adjuvant endocrine therapy.

    Treatment with Aromasin should continue until tumor progression is evident for patients with advanced breast cancer.

  • What should I avoid while taking Aromasin?

    Avoid alcohol, smoking, and drinks with caffeine such as tea, coffee, and soda.
  • What are possible food and drug interactions associated with Aromasin?

    If Aromasin is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Aromasin with the following: co-medications that induce CYP 3A4 (such as rifampicin, phenytoin, carbamazepine, phenobarbital, or St. Johns wort). These medications may significantly decrease exposure to exemestane.
  • What are the possible side effects of Aromasin?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: hot flashes, feeling tired, joint pain, headache, inability to sleep, increased sweating, nausea,.visual disturbances, depression, increased blood pressure, hair loss, diarrhea, muscle pain

  • Can I receive Aromasin if I am pregnant or breastfeeding?

    The effects of Aromasin during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    Do not take Aromasin if you are pregnant. Aromasin may cause birth defects or even death to an unborn baby.

  • What should I do if I miss a dose of Aromasin?

    If you miss a dose, take the next dose as usual. Do not double your next dose. Do not make up the missed dose.
  • How should I store Aromasin?

    Store in a cool, dry place, away from sunlight or heat in a tightly sealed container.