Avelox

Generic Name: Moxifloxacin

  • What is Avelox?

    Avelox is an antibiotic used to treat bacterial infections such as sinus infection, pneumonia, secondary infections in chronic bronchitis (a long term inflammation present in the lungs), skin infections, and abdominal infections. Like all antibiotics, Avelox works only against bacteria. It will not cure an infection caused by a virus, such as the common cold or flu.

  • What is the most important information I should know about Avelox?

    In rare cases, antibiotics can cause a serious allergic reaction. Stop taking Avelox and call your doctor immediately if you develop any of the following warning signs: skin rash, tingling, hives, swelling of the face or throat, difficulty breathing or swallowing, rapid heartbeat, or yellowing of the skin or eyes.

    A rare but serious side effect of Avelox is tendon rupture or swelling of the tendon. Stop taking Avelox and call you doctor immediately if you notice any tendon pain, swelling, or inflammation.

    Avelox may cause a rare heart problem called QT prolongation. If you are being treated for an abnormal heartbeat, make sure the doctor is aware of it. You may have to avoid Avelox. Also tell the doctor if you or anyone in your family has a history of heart problems. If you develop a change in heartbeat or fainting spells while taking Avelox, contact your doctor immediately.

    Avelox may cause damage to nerves in the arms, hands, legs, or feet. Tell your doctor immediately if you experience any of the following warning signs: pain, burning, tingling, numbness, or weakness.

    Avelox may make your skin more sensitive to light.

    Mild diarrhea is common with antibiotic use. However, a more serious form of diarrhea, although rare, may occur. Contact your doctor right away if you experience stomach pain or cramps, severe diarrhea, or bloody stools. Do not treat the diarrhea without first checking with your doctor.

  • Who should not take Avelox?

    Do not use Avelox if you are allergic to any of its ingredients or if you have had an allergic reaction to a quinolone antibiotic (such as ciprofloxacin and levofloxacin).

  • What should I tell my doctor before I take the first dose of Avelox?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Avelox. Also, talk to your doctor about your complete medical history, especially if you have tendon or joint problems, have a history of seizures, have a heart problem, are being treated for an abnormal heartbeat, have a history of convulsions or blockage of arteries in the brain, diarrhea, or skin sensitivity to the sun. Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Bacterial Sinus Infection

    Adults: The usual dose is one 400-milligram (mg) tablet daily for 10 days.

    Chronic Bronchitis

    Adults: The usual dose is one 400-mg tablet daily for 5 days.

    Pneumonia

    Adults: The usual dose is one 400-mg tablet daily for 7-14 days.

    Abdominal Infections

    Adults: The usual dose is one 400-mg tablet daily for 5-14 days.

    Skin Infections

    Adults: The usual dose is one 400-mg tablet daily for 7-21 days.

  • How should I take Avelox?

    Take Avelox at the same time each day. Avelox may be taken with or without food. Be sure to drink plenty of fluids while taking Avelox. It's important to take the full dosage schedule of Avelox, even if you're feeling better in a few days. Not completing the full dosage schedule may decrease the drug's effectiveness and increase the chances that the bacteria may become resistant to Avelox and similar antibiotics. If this happens, Avelox and similar antibiotics may not work in the future.

    Avelox should be taken at least 4 hours before or 8 hours after aluminum-, magnesium-, or calcium-containing antacids, sucralfate, multivitamins with iron or zinc, and didanosine chewable/buffered tablets or oral solution.

  • What should I avoid while taking Avelox?

    Avelox may make you dizzy or light-headed. Do not drive a car, operate machinery, or engage in activities requiring mental alertness or coordination until you know how Avelox affects you.

    Avoid sunlamps, tanning beds, and limit your time in the sun, as Avelox can make your skin more sensitive to light and cause sunburns. Wear sunscreen or protective clothing if you are going to be outside for long periods.

  • What are possible food and drug interactions associated with Avelox?

    If Avelox is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Avelox with the following: amiodarone, antipsychotic drugs, cisapride, didanosine, erythromycin, multivitamins containing iron or zinc, nonsteroidal anti-inflammatory drugs (NSAIDs), procainamide, quinidine, sotalol, sucralfate, tricyclic antidepressants, warfarin, and antacids containing magnesium, calcium, or aluminum.

  • What are the possible side effects of Avelox?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: abdominal pain, anxiety, diarrhea, dizziness, drowsiness, headache, insomnia, joint and muscle pain, nausea, nervousness, rapid heartbeat, rash, sweating, tendon rupture or swelling, vomiting

  • Can I receive Avelox if I am pregnant or breastfeeding?

    The effects of Avelox during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Avelox?

    If you miss a dose of Avelox, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular schedule. Do not take more than one dose of Avelox in 1 day.

  • How should I store Avelox?

    Store Avelox at room temperature. Avoid high humidity.

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I'm Beth Isaac, PharmD. Welcome to PDR Health!

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