Generic Name: Norethindrone acetate

  • What is Aygestin?

    Aygestin contains a type of hormone known as progesterone. It is used to restore menstruation in women who have stopped having menstrual cycles (also called amenorrhea). Aygestin can also help treat endometriosis, a condition where the endometrium (the lining of the uterus) doesn't shed properly and attaches to the outside of the uterus or other areas such as the ovaries or bowels. Aygestin also helps control unusual and heavy bleeding of the uterus caused by hormonal imbalance. However, the drug is not used to control bleeding caused by fibroids or cancer.
  • What is the most important information I should know about Aygestin?

    Aygestin increases the risk of blood clots, which can lead to phlebitis, breathing problems, vision problems, or stroke. If you experience any symptoms that might suggest the onset of a clot-related disorder—pain with swelling, warmth and redness in a leg vein, coughing or shortness of breath, loss of vision or double vision, migraine, or weakness or numbness in an arm or leg—stop taking Aygestin and see your doctor immediately.
  • Who should not take Aygestin?

    Do not take Aygestin if you have ever had an allergic reaction to it. Do not take Aygestin if you are pregnant or have had an incomplete miscarriage. Avoid it if you have ever had a blood clotting disorder or a stroke. Do not take this drug if you have breast cancer, unexplained vaginal bleeding, or severe liver disease. Aygestin should not be used to test for pregnancy.
  • What should I tell my doctor before I take the first dose of Aygestin?

    Tell your doctor about all prescription, over-the-counter, and herbal medication you are taking before beginning treatment with Aygestin. Also, talk to your doctor about your complete medical history, especially if you have epilepsy, migraines, asthma, or a heart or kidney problem. Also, tell your doctor if you have diabetes, high cholesterol, or if you have have suffered from depression in the past.
  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Prevention of abnormal uterine bleeding due to hormonal imbalance or to restore menstrual periods

    Adults: The usual dose is 2.5 to 10 milligrams (mg) a day taken for 5 to 10 days during the second half of a 28-day cycle. Your period should start 3 to 7 days after you stop taking Aygestin.

    Treatment of endometriosis

    The recommended starting dose is 5 mg a day for 2 weeks. The doctor may increase your dose by 2.5 mg a day every 2 weeks up to a maximum of 15 mg a day. Treatment may continue for 6 to 9 months or until intolerable breakthrough bleeding occurs.

  • How should I take Aygestin?

    Take Aygestin as directed by your doctor.
  • What should I avoid while taking Aygestin?

    Avoid becoming pregnant while taking Aygestin. This drug may cause harm to a developing baby.
  • What are possible food and drug interactions associated with Aygestin?

    If Aygestin is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Aygestin with the following: aminoglutethimide, carbamazepine, phenobarbital, phenytoin, rifabutin, and rifampin.
  • What are the possible side effects of Aygestin?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: acne, allergic reaction, blood clots, breakthrough menstrual bleeding, breast enlargement or tenderness, bulging eye, depression, double vision, change in menstrual flow, headache, hives, menstrual spotting, migraine, mood swings, nausea, rash with or without itchy spots, skin discoloration, sleeplessness, stopping of menstrual flow, swelling, vision loss, weight increase or decrease, yellowing of the skin or eyes

  • Can I receive Aygestin if I am pregnant or breastfeeding?

    Do not take Aygestin if you are pregnant or trying to become pregnant, since the drug may cause harm to a developing baby.

    Aygestin appears in breast milk. Because the effect of Aygestin on a nursing infant is unknown, it is best to avoid the drug while breastfeeding unless it's clearly necessary.

  • What should I do if I miss a dose of Aygestin?

    Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never take 2 doses at the same time.
  • How should I store Aygestin?

    Store at room temperature in a tightly closed container.