Generic Name: Norethindrone

  • What is Aygestin?

    Aygestin is a medicine containing norethindrone acetate, a hormone known as progesterone. It is used to restore menstruation in women who have stopped having a period for about 3 cycles, and to treat endometriosis, a common gynecological disorder that may result in sores and pain. Aygestin also helps control unusual and heavy bleeding of the uterus caused by hormone imbalance.

  • What is the most important information I should know about Aygestin?

    Aygestin increases your risk of a blood clot in the leg, lung, heart, brain, or eye. If you experience any of the following symptoms of a clot-related disorder, stop taking Aygestin and see your doctor immediately: pain with swelling, warmth and redness in a leg, coughing or shortness of breath, loss of vision or double vision, migraine, or weakness or numbness in an arm or leg.

    Progestin therapy can affect the way your body processes fat and sugar. Women with diabetes, high cholesterol, or high triglycerides should be monitored closely.

    Make sure your doctor knows if you have ever been diagnosed with depression. You may need to discontinue Aygestin if depression reoccurs.

    Contact your doctor if you experience any breakthrough, unusual, or irregular bleeding while on this medication.

    Aygestin can cause fluid retention, which may impact individuals with seizures, migraines, or heart or kidney problems. Patients with these conditions require careful monitoring.

  • Who should not take Aygestin?

    Do not take Aygestin if you have ever had an allergic reaction to it. Do not take Aygestin if you are pregnant, plan to become pregnant, are breastfeeding, or have had an incomplete miscarriage. Avoid this drug if you have ever had a blood clotting disorder. Do not take this drug if you have breast cancer, unexplained vaginal bleeding, severe liver disease, or are postmenopausal.

  • What should I tell my doctor before I take the first dose of Aygestin?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Aygestin. Also, talk to your doctor about your complete medical history, especially if you have seizures, migraines, asthma, or a heart or kidney problem. Also, tell your doctor if you have diabetes, high cholesterol, or if you have suffered from depression.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Prevention of Abnormal Uterine Bleeding due to Hormonal Imbalance or to Restore Menstrual Periods

    Adults: The usual dose is 2.5 milligrams (mg) to 10 mg once a day, taken for 5-10 days during the second half of a 28-day menstrual cycle. Your period should start 3-7 days after you stop taking Aygestin.

    Treatment of Endometriosis

    Adults: The recommended starting dose is 5 mg once daily for 2 weeks. Treatment can continue for 6-9 months.

  • How should I take Aygestin?

    Take Aygestin as directed by your doctor.

  • What should I avoid while taking Aygestin?

    Avoid becoming pregnant while taking Aygestin. This drug may cause harm to an unborn baby.

  • What are possible food and drug interactions associated with Aygestin?

    If Aygestin is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is important to check with your doctor before combining Aygestin with any other medication.

  • What are the possible side effects of Aygestin?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: breakthrough menstrual bleeding, breast pain, change in menstrual flow, depression, fluid retention, hair loss, headache, high blood pressure, menstrual spotting, nausea, stomach pain/bloating/cramping, stopping of menstrual flow, vaginal yeast infections

  • Can I receive Aygestin if I am pregnant or breastfeeding?

    Do not take Aygestin if you are pregnant or plan to become pregnant, since the drug may cause harm to an unborn baby. Aygestin appears in breast milk. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Aygestin?

    If you miss a dose of Aygestin, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store Aygestin?

    Store at room temperature.