Generic Name: Rufinamide

  • What is Banzel?

    Banzel is a medicine used with other medicines to treat seizures associated with Lennox-Gastaut syndrome (LGS). Banzel is available in tablets and an oral suspension.

  • What is the most important information I should know about Banzel?

    Do not stop taking Banzel without first talking to your doctor. Stopping Banzel suddenly can cause serious problems, including seizures that will not stop (status epilepticus).

    Banzel can cause suicidal thoughts or actions. Tell your doctor immediately if you have thoughts about suicide or dying; attempt to commit suicide; have new or worse depression, anxiety, or irritability; have panic attacks; have trouble sleeping (insomnia); have an extreme increase in activity and talking (mania); are feeling agitated or restless; acting aggressive; being angry or violent; acting on dangerous impulses; or have other unusual changes in behavior or mood. Tell your doctor immediately if you have any of these symptoms.

    Banzel can make you feel dizzy, have double vision, feel sleepy, or have problems with coordination and walking. Do not drive, operate heavy machinery, or do other dangerous activities until you know how Banzel affects you.

    Banzel can also cause allergic reactions or serious problems that can affect organs, including the liver or blood cells. Contact your doctor immediately if you experience a skin rash, fever, swollen lymph nodes (glands found throughout the body that remove bacteria and play an important role in your immune system), sore throat, yellowing of your skin or whites of your eyes, dark urine, unusual bruising or bleeding, severe tiredness or weakness, severe muscle pain, trouble swallowing or breathing, or swelling of your face, eyes, lips, or tongue.

  • Who should not take Banzel?

    Do not take Banzel if you are allergic to it or any of its ingredients, or if you have a genetic condition called familial short QT syndrome (an abnormal heart rhythm).

  • What should I tell my doctor before I take the first dose of Banzel?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Banzel. Also, talk to your doctor about your complete medical history, especially if you have or had heart problems, liver problems, suicidal thoughts or actions, depression, mood problems, or are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: The recommended dose is 200-400 milligrams (mg) twice a day. Your doctor will increase your dose as needed, until the desired effect is achieved.

    Children ≥4 years: Your doctor will prescribe the appropriate dose for your child, based on their weight.

    Attempts to taper or discontinue the medication should be made at specific intervals, through the guidance of your doctor.

  • How should I take Banzel?

    Take Banzel exactly as prescribed by your doctor. You can take Banzel with food. Do not change your dose or stop taking this medication abruptly without first speaking to your doctor.

    Banzel tablets can be swallowed whole, cut in half, or crushed.

    Shake the Banzel oral suspension well before you take each dose. Measure your dose using the bottle adapter or dosing syringes provided. Please review the instructions that came with your prescription on how to properly use Banzel oral suspension.

  • What should I avoid while taking Banzel?

    Do not drink alcohol or take other medicines that make you sleepy or dizzy while you are taking Banzel until you talk to your doctor. Doing so can make your sleepiness or dizziness worse.

    Do not drive, operate heavy machinery, or engage in dangerous activities until you know how Banzel affects you.

  • What are possible food and drug interactions associated with Banzel?

    If Banzel is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Banzel with the following: birth control pills, chlorzoxazone, other seizure medications (such as carbamazepine, phenobarbital, phenytoin, primidone, or valproate), or triazolam.

  • What are the possible side effects of Banzel?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: allergic reactions, dark urine, dizziness, headache, muscle pain, nausea, seizures, sleepiness, tiredness, vomiting, weakness, yellowing of your skin or whites of your eyes

  • Can I receive Banzel if I am pregnant or breastfeeding?

    The effects of Banzel during pregnancy and breastfeeding are unknown. Banzel can be found in your breast milk if you take it while breastfeeding. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Banzel?

    If you miss a dose of Banzel, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store Banzel?

    Store at room temperature.

    Keep the tablets in a dry place.

    Keep the oral suspension in an upright position and secure the cap after opening. Use the oral suspension within 90 days of first opening the bottle.