Biafine

Generic Name: Ethylene glycol

  • What is Biafine?

    Biafine is a topical emulsion (applied directly on the skin) used to treat wounds, abrasions, or full thickness wounds, or to manage skin graft (transplant) sites and donor sites. Biafine is also used to treat burns, including sunburns, on your skin or inflammation of your skin due to radiation therapy. Biafine provides a moist environment that is beneficial to the healing process of the wound, and it isolates the wound from getting contaminated.

  • What is the most important information I should know about Biafine?

    Biafine is for external use only. Do not take this medication by mouth.

    Biafine does not contain a sunscreen. Do not use Biafine prior to extended exposure to the sun.

    Contact your doctor if your condition worsens or does not improve after 10-14 days of using Biafine. Also, contact your doctor if you get a skin infection.

    If you use Biafine prior to radiation, do not apply it anytime within the 4 hours before your radiation session.

  • Who should not take Biafine?

    Do not use Biafine if you are allergic to it or any of its ingredients. Also, do not use Biafine if you have bleeding wounds, or if you have skin rashes related to food or medicine allergies.

  • What should I tell my doctor before I take the first dose of Biafine?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Biafine. Also, talk to your doctor about your complete medical history, especially if you have a skin infection.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Wounds, Abrasions, or Full Thickness Wounds

    Adults: Apply thick 1/4-1/2 inch layers on and around the affected area(s) every 24-48 hours or as needed.

    Donor Site Management

    Adults: Apply to the affected area(s) after the skin removal and cover with a moist dressing.

    Skin Graft Site Management

    Adults: Apply to the graft site(s) only after the graft has taken successfully.

    Burns, Including Sunburns

    Adults: Apply thick 1/4-1/2 inch layers on and around the affected area(s) continuously as needed.

    Radiation Skin Inflammation

    Adults: Apply the emulsion to the affected area(s) 3 times a day, 7 days a week, continuously as needed.

  • How should I take Biafine?

    Apply Biafine exactly as prescribed by your doctor.

    For the treatment of wounds, abrasions, or full thickness wounds, wash the affected area(s) with saline, clean water, or a suitable wound cleanser. If you are applying gauze dressing, lightly moisten the dressing before application.

    For donor site management, cover the treated area(s) with a moist dressing, and reapply as needed. In addition, for skin graft site management, Biafine emulsion can be washed away with a saline solution or clean water without causing damage to the newly formed tissues.

    For the treatment of burns, be cautious when you remove any clothing in the affected area(s). After applying a thick layer of the emulsion, a white residue may remain. Apply thinner layers of Biafine emulsion if pain from the burn persists.

    For the treatment of skin inflammation due to radiation, massage Biafine emulsion gently into your skin.

  • What should I avoid while taking Biafine?

    Do not take Biafine by mouth.

    Do not excessively expose your skin to the sun.

  • What are possible food and drug interactions associated with Biafine?

    No significant interactions have been reported with Biafine at this time. However, always tell your doctor about any medicines you take, including over-the-counter medications, vitamins, and herbal supplements.

  • What are the possible side effects of Biafine?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: allergic reactions, tingling sensation

  • Can I receive Biafine if I am pregnant or breastfeeding?

    The effects of Biafine during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Biafine?

    If you miss a dose of Biafine, apply it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not apply two doses at once.

  • How should I store Biafine?

    Store at room temperature. Do not freeze.