Brilinta

Generic Name: Ticagrelor

  • What is this medication and its most common uses?

    Brilinta is a medicine used to treat people who have had a heart attack or severe chest pain due to heart problems, and those who are being treated with medicines or a procedure to open blocked arteries in the heart.

  • What should I know when beginning and continuing on this medication?

    How does this medication work?

    Blood clots form when certain blood cells, called platelets, clump together. Brilinta works by making platelets in the blood less sticky, so they are less likely to clump together and form blood clots.

    What are the beneficial effects of this medication and when should I begin to have results?

    What: Brilinta, in combination with aspirin, helps lower your chance of having another serious problem with your heart or blood vessels, such as another heart attack, a stroke, or blood clots in your stent.

    When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you take Brilinta exactly as your healthcare provider has prescribed.

    How do I know it is working?

    Your healthcare provider will monitor you regularly to check how well this medication is working.

  • What are the possible side effects of this medication?

    The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

    Brilinta can cause bleeding that can be serious and sometimes life-threatening. You may have a higher risk of bleeding if you take Brilinta and are elderly; have a stomach ulcer, trauma (such as an accident or surgery), or stomach or intestinal bleeding that is recent or keeps coming back; or also take other medicines that increase your risk of bleeding (such as heparin, nonsteroidal anti-inflammatory drugs [NSAIDs] [such as ibuprofen or naproxen], warfarin, or other medicines to prevent or treat blood clots).

    Call your healthcare provider right away if you experience unusual bruising (bruises that develop without known cause or grow in size), nosebleeds, bleeding from cuts that takes a long time to stop, pink or brown urine, red or black stools, coughing up blood, or vomiting blood or material that looks like coffee grounds.

    Brilinta is taken with aspirin. Talk to your healthcare provider about the dose of aspirin that you should take with Brilinta. Do not take a dose of aspirin higher than 100 milligrams (mg) a day, because it can affect how well Brilinta works. Do not take doses of aspirin higher than what your healthcare provider tells you to take. Tell your healthcare provider if you take other medicines that contain aspirin, including over-the-counter medicines.

    More common side effects may include: bleeding, shortness of breath.

  • Who should not take this medication?

    Do not take Brilinta if you are allergic to it or any of its ingredients.

    Do not take Brilinta if you currently have abnormal bleeding (such as stomach or intestinal bleeding) or a history of bleeding in your brain.

    Do not take Brilinta if you have severe liver problems.

  • What should I tell my healthcare provider before I take the first dose of this medication?

    Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Brilinta. Also, talk to your healthcare provider about your complete medical history, especially if you have bleeding, liver, or lung (such as chronic obstructive pulmonary disease [COPD] or asthma) problems; a history of stomach ulcers, colon polyps (non-cancerous growths on the surface of the colon), or stroke; any recent severe injury or surgery; if you plan to have surgery (such as a heart bypass) or a dental procedure; or if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

    Adults: The recommended dose is 90 mg twice a day. Your healthcare provider will give you a single 180-mg dose (two 90-mg tablets) before having you take 90 mg twice a day.

    It is important that you do not stop taking this medication abruptly. If you need to change or stop taking this medication, it is important that you only do this with the guidance of your healthcare provider.

  • How should I take this medication?

    Take Brilinta exactly as prescribed by your healthcare provider. Do not change your dose or stop taking Brilinta without first talking to your healthcare provider.

    Take Brilinta with or without food.

    Take Brilinta with aspirin as instructed by your healthcare provider.

  • What should I avoid while taking this medication?

    Do not stop taking Brilinta without first talking to your healthcare provider. Stopping Brilinta earlier than recommended may increase your risk of heart problems.

    Do not take over-the-counter medicines that contain aspirin without first talking to your healthcare provider.

  • What are the possible food and drug interactions associated with this medication?

    If Brilinta is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Brilinta with the following: atazanavir, carbamazepine, clarithromycin, dexamethasone, digoxin, indinavir, itraconazole, ketoconazole, lovastatin, nefazodone, nelfinavir, phenobarbital, phenytoin, rifampin, ritonavir, saquinavir, simvastatin, telithromycin, or voriconazole.

  • May I receive this medication if I am pregnant or breastfeeding?

    The effects of Brilinta during pregnancy and breastfeeding are unknown. Do not breastfeed while you are taking Brilinta. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of this medication?

    If you miss a dose of Brilinta, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store this medication?

    Store at room temperature.