Butorphanol Spray

Generic Name: Butorphanol

  • What is Butorphanol Spray?

    Butorphanol spray is a narcotic pain medicine used to manage pain. Butorphanol comes in the form of a nasal (nose) solution.

    Butorphanol is a federally controlled substance because it has abuse potential.

  • What is the most important information I should know about Butorphanol Spray?

    Butorphanol has abuse potential. Mental and physical dependence can occur with the use of butorphanol when it is used improperly for long periods of time.

    Butorphanol can impair your mental and physical abilities. Do not drive or operate machinery until you know how butorphanol affects you. Also, do not drink alcohol or take other medications that can affect your brain function (such as medications that make you drowsy and narcotic painkillers) while using butorphanol.

  • Who should not take Butorphanol Spray?

    Do not use butorphanol if you are allergic to it, any of its ingredients, or to the preservative benzethonium chloride.

  • What should I tell my doctor before I take the first dose of Butorphanol Spray?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with butorphanol. Also, talk to your doctor about your complete medical history, especially if you have breathing problems; brain problems or head injury; liver or kidney problems; heart problems or low blood pressure; history of or a present drug abuse or addiction problem; a family history of drug abuse or addiction problem; are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: The recommended starting dose is one 1-milligram (mg) spray into one nostril. Your doctor may adjust the dose for you based on your condition.

  • How should I take Butorphanol Spray?

    Use butorphanol exactly as prescribed by your doctor. You must prime (to release into the air the dose that is already in the device) the nasal spray unit before using it the first time and if it has not been used for 48 hours or longer. Do not use butorphanol more often or in larger doses than instructed by your doctor. If prescribed by your doctor, you can take a second spray 60-90 minutes after the first if needed for pain relief. You can repeat this sequence every 3-4 hours as needed for pain. If your doctor prescribes a 2-mg dose, spray 1 spray into each nostril.

    Please review the instructions that came with your prescription on how to properly use butorphanol.

  • What should I avoid while taking Butorphanol Spray?

    Do not drive or operate machinery until you know how butorphanol affects you.

    Do not drink alcohol or take other medications that can affect your brain while using butorphanol.

    Do not spray butorphanol into both nostrils unless prescribed by your doctor.

  • What are possible food and drug interactions associated with Butorphanol Spray?

    If butorphanol is used with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining butorphanol with the following: alcohol, antihistamines (such as diphenhydramine), or other medications that slow down your brain function (such as alprazolam or phenobarbital).

  • What are the possible side effects of Butorphanol Spray?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: chest pain, depression, difficulty breathing, difficulty sleeping, dizziness, drowsiness, headache, high blood pressure, irregular heartbeat, nasal congestion, nausea, shallow breathing, shortness of breath, swelling, vomiting

  • Can I receive Butorphanol Spray if I am pregnant or breastfeeding?

    The effects of butorphanol during pregnancy and breastfeeding are unknown. Butorphanol can be found in your breast milk if you use it while breastfeeding. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Butorphanol Spray?

    Butorphanol should be given under special circumstances determined by your doctor.

  • How should I store Butorphanol Spray?

    Store at room temperature. Protect from light.