Capozide

Generic Name: Captopril

  • What is Capozide?

    Capozide contains two medicines: captopril, an angiotensin-converting enzyme (ACE) inhibitor, and hydrochlorothiazide, a diuretic. These two medications work together to lower blood pressure.

  • What is the most important information I should know about Capozide?

    If you get pregnant, stop taking Capozide and call your doctor right away. Capozide can harm an unborn baby, causing injury and even death. If you plan to become pregnant, talk to your doctor about other treatment options before taking Capozide.

    Do not discontinue Capozide, unless your doctor tells you to.

    If you experience angioedema (e.g., swelling of the face, eyes, lips, tongue, larynx, and extremities, difficulty in swallowing or breathing, or hoarseness), contact your doctor and discontinue Capozide.

    If you feel any signs of infection (e.g., sore throat or fever), tell your doctor.

    Avoid rapid increases in exercise or physical activity if you have heart failure.

  • Who should not take Capozide?

    Do not take Capozide if you are allergic to captopril, any other ACE inhibitor, hydrochlorothiazide, or any of its ingredients.

    Do not take Capozide if you have trouble urinating or if you are allergic to medicines that contain sulfonamides.

    Do not take Capozide if you are pregnant. If you get pregnant, stop taking Capozide and call your doctor right away. Capozide can harm an unborn child.

  • What should I tell my doctor before I take the first dose of Capozide?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Capozide. Also, talk to your doctor about your complete medical history, especially if you have heart failure, a connective tissue disease called lupus erythematosus, kidney disease, liver disease, cases of angioedema (swelling of the face), or if you are on dialysis.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: Your doctor will determine the dose based on your response. Dosages are also adjusted for people with kidney problems.

    The initial dose is one tablet containing 25 milligrams (mg) captopril/15 mg hydrochlorothiazide, once a day. If this is not effective, your doctor may increase the dose every 6 weeks. In general, the daily dose of captopril should not exceed 150 mg. The maximum recommended daily dose of hydrochlorothiazide is 50 mg. Your doctor may prescribe a lower dose if you have kidney disease.

  • How should I take Capozide?

    Take Capozide 1 hour before meals.

  • What should I avoid while taking Capozide?

    Do not stop taking Capozide unless your doctor tells you to.

    Patients with heart failure should not increase their physical activity too quickly.

    Do not use potassium-sparing diuretics, potassium supplements, or potassium-containing salt substitutes without talking to your doctor.

  • What are possible food and drug interactions associated with Capozide?

    If Capozide is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Capozide with the following: alcohol; antigout drugs, such as allopurinol; amphotericin B; aspirin; barbiturates; calcium; cardiac glycosides; cholestyramine; colestipol; diazoxide; digoxin; corticosteroids, such as prednisone; corticotropin (ACTH); diabetes drugs, such as glyburide or insulin; gold; lithium; MAO inhibitors, such as phenelzine; methenamine; narcotics; nitroglycerin or other nitrates; nonsteroidal anti-inflammmatory drugs, such as naproxen; narcotics; norepinephrine and other pressor amines; oral blood thinners, such as warfarin; other blood pressure drugs; diuretics (eg, potassium-sparing diuretics, such as spironolactone, triamterene, amiloride); potassium supplements; probenecid; sulfinpyrazone; and vasodilators.

  • What are the possible side effects of Capozide?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: itching, loss of taste, low blood pressure, rash, chest pain, nausea, vomiting, dizziness, headache, diarrhea

  • Can I receive Capozide if I am pregnant or breastfeeding?

    If you become pregnant while taking Capozide, stop taking it and call your doctor right away. Capozide can harm an unborn baby, causing injury and even death. If you plan to become pregnant, talk to your doctor about other treatment options before taking Capozide. Capozide may pass through your breast milk and cause harm. Avoid breastfeeding if you are taking Capozide.

  • What should I do if I miss a dose of Capozide?

    If you miss a dose, take it as soon as you remember. If it is close to your next dose, do not take the missed dose. Just take the next dose at your regular time.

  • How should I store Capozide?

    Store at room temperature in a tightly closed container, away from moisture.

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