Cardizem LA

Generic Name: Diltiazem

  • What is this medication and its most common uses?

    Cardizem LA is a medicine, known as a calcium channel blocker, which is used alone or in combination with other medicines, to treat high blood pressure and angina (chest pain).

  • What should I know when beginning and continuing on this medication?

    How does this medication work?

    Cardizem LA is an extended-release medicine, which releases medicine into your body throughout the day. Cardizem LA lowers blood pressure by relaxing your blood vessels, which allows your blood to flow through with less resistance. Cardizem LA also helps to reduce chest pain by increasing the supply of oxygen delivered to your heart and reducing the workload of your heart.

    What are the beneficial effects of this medication and when should I begin to have results?

    What: By lowering your blood pressure, Cardizem LA may lower your risk of a stroke or a heart attack. Cardizem LA may help manage your symptoms of chest pain. Also, it is taken just once a day, which may make it easier for you to remember.

    When: Cardizem LA may lower your blood pressure within 14 days. Though you may not feel an improvement or change in the way you feel, it is very important to keep taking your medicine as prescribed to keep your condition under control.

    How do I know it is working?

    Check your blood pressure regularly. Your healthcare provider will also check your blood pressure and your symptoms at every visit. Following an appropriate diet and exercise plan will also affect your blood pressure results.

  • What are the possible side effects of this medication?

    The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

    More common side effects may include: swelling of your legs, ankles, or feet; dizziness; fatigue; slow heartbeat; cough.

    Less common side effects may include:

    Risk of having a very slow heart rate, worsened congestive heart failure (a condition in which the heart cannot pump enough blood throughout the body), low blood pressure, or liver injury.

    Skin reactions (such as petechiae [tiny, pinpoint, red dots], light sensitivity, itching, or hives) can occur with Cardizem LA and can disappear.

  • Who should not take this medication?

    Do not take Cardizem LA if you are allergic to it or any of its ingredients.

    Do not take Cardizem LA if you have low blood pressure.

    Do not take Cardizem LA if you have sick sinus syndrome (abnormal heart rhythm) or a heart block, unless you have a pacemaker.

    Do not take Cardizem LA if you have recently had a heart attack and lung congestion (a buildup of fluid in the lungs).

  • What should I tell my healthcare provider before I take the first dose of this medication?

    Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Cardizem LA. Also, talk to your healthcare provider about your complete medical history, especially if you have heart problems (such as heart failure or abnormal heart rhythms), kidney or liver disease, low blood pressure, a recent history of heart attack, or if you are pregnant, plan to become pregnant, or are breastfeeding.

    Also, talk to your healthcare provider about any planned surgeries or procedures.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

    High Blood Pressure

    Adults: The usual starting dose is 180-240 milligrams (mg) once a day. Your healthcare provider may adjust your dose as needed, until the desired effect is achieved.


    Adults: The usual starting dose is 180 mg once a day. Your healthcare provider may adjust your dose as needed, until the desired effect is achieved.

  • How should I take this medication?

    Take Cardizem LA exactly as prescribed by your healthcare provider.

    Take Cardizem LA at about the same time once each day either in the morning or at bedtime.

    Swallow Cardizem LA tablets whole. Do not crush or chew them.

    Take Cardizem LA with or without food.

  • What should I avoid while taking this medication?

    Do not change your dose or stop taking Cardizem LA without first talking to your healthcare provider.

  • What are the possible food and drug interactions associated with this medication?

    If Cardizem LA is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Cardizem LA with the following: blood pressure/heart medications known as beta-blockers (such as atenolol or propranolol), buspirone, carbamazepine, cholesterol-lowering medications known as statins (such as lovastatin or simvastatin), cimetidine, clonidine, cyclosporine, digoxin, midazolam, quinidine, rifampin, or triazolam.

  • May I receive this medication if I am pregnant or breastfeeding?

    The effects of Cardizem LA during pregnancy are unknown. Cardizem LA can be found in your breast milk if you take it while breastfeeding. Do not take Cardizem LA while you are breastfeeding. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of this medication?

    If you miss a dose of Cardizem LA, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store this medication?

    Store at room temperature. Protect from light and humidity.