Generic Name: Methsuximide

  • What is Celontin?

    Celontin is a medicine used to treat absence (petit mal) seizures that have not gotten better with other seizure medicines.

  • What is the most important information I should know about Celontin?

    Do not stop taking Celontin without first talking to your doctor. Stopping Celontin suddenly can cause serious problems, including seizures that will not stop (status epilepticus).

    Celontin can cause rare but serious blood problems that may be life-threatening. Contact your doctor immediately if you experience a fever, swollen lymph nodes (glands found throughout the body that remove bacteria and play an important role in your immune system), sore throat that comes and goes or does not go away, frequent infections or an infection that does not go away, easy bruising, red or purple spots on your body, bleeding gums or nose bleeds, or severe tiredness or weakness.

    Celontin can also cause lupus (disease that affects the immune system). Contact your doctor immediately if you experience joint pain and swelling, muscle pain, fatigue, low-grade fever, pain in your chest that is worse with breathing, or unexplained skin rash.

    Celontin can cause suicidal thoughts or actions. Tell your doctor immediately if you have thoughts about suicide or dying; attempt to commit suicide; have new or worse depression, anxiety, or irritability; have panic attacks; have trouble sleeping (insomnia); have an extreme increase in activity and talking (mania); are feeling agitated or restless; acting aggressive; being angry or violent; acting on dangerous impulses; or have other unusual changes in behavior or mood.

    Tell your doctor immediately if you develop signs and symptoms of infection, including sore throat or fever, while you are taking Celontin.

  • Who should not take Celontin?

    Do not take Celontin if you are allergic to it, any of its ingredients, or similar medications (such as ethosuximide).

  • What should I tell my doctor before I take the first dose of Celontin?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Celontin. Also, talk to your doctor about your complete medical history, especially if you have or had liver problems; depression, mood problems, or suicidal thoughts or behavior; or if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults and children: The recommended starting dose is 300 milligrams (mg) a day for 1 week. Your doctor will increase your dose as needed, until the desired effect is achieved.

  • How should I take Celontin?

    Take Celontin exactly as prescribed by your doctor. Do not change your dose or stop taking this medication abruptly without first talking to your doctor.

  • What should I avoid while taking Celontin?

    Do not drink alcohol or take other medicines that make you sleepy or dizzy while you are taking Celontin. Doing so can make your sleepiness or dizziness worse.

    Do not drive, operate heavy machinery, or engage in dangerous activities until you know how Celontin affects you. Celontin can slow your thinking and motor skills.

  • What are possible food and drug interactions associated with Celontin?

    If Celontin is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Celontin with other seizure medications (such as phenobarbital or phenytoin).

  • What are the possible side effects of Celontin?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: blurred vision, constipation, diarrhea, dizziness, drowsiness, headache, loss of appetite, nausea, problems with your walking and coordination, seizures, stomach pain, vomiting, weight loss

  • Can I receive Celontin if I am pregnant or breastfeeding?

    The effects of Celontin during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Celontin?

    If you miss a dose of Celontin, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store Celontin?

    Store at room temperature. Keep Celontin in a dry place out of the light and protect from heat.