Cesamet

Generic Name: Nabilone

  • What is Cesamet?

    Cesamet is used to treat nausea and vomiting that result after chemotherapy treatment in patients who have failed to respond adequately to other anti-nausea treatments.

  • What is the most important information I should know about Cesamet?

    Cesamet should be used with caution in the elderly and those with high blood pressure or heart disease. Cesamet should also be used with caution in patients with psychiatric disorders (including manic depressive illness, depression, and schizophrenia); disease symptoms may return with the use of this drug.

    The effects of Cesamet may last for an indefinite time period after taking by mouth. Adverse psychiatric effects can last for 48-72 hours after stopping treatment. Cesamet may cause dizziness, drowsiness, euphoria or a "high" feeling, poor coordination, anxiety, disorientation, depression, hallucinations, and psychosis. Patients using Cesamet must be under close supervision of a responsible adult, especially when starting or changing the dose.

    Taking Cesamet for long periods of time may cause dependence or addiction. If you stop taking Cesamet suddenly, you may experience withdrawal symptoms which include distress, hiccups, loose stools, runny nose, sweating, and trouble sleeping.

  • Who should not take Cesamet?

    You should not take Cesamet if you are allergic to any cannabinoids such as dronabinol.

  • What should I tell my doctor before I take the first dose of Cesamet?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Cesamet. Also, talk to your doctor about your complete medical history, especially if you have a history of high or low blood pressure, heart disease, irregular or fast heart beat, liver or kidney problems, mental or mood disorders (including depression, bipolar disorder, schizophrenia), a history or a family history of alcohol abuse, drug abuse, or dependence, or if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: The usual dose is 1-2 milligrams (mg) two times a day. It may be given two to three times a day during the entire course of each cycle of chemotherapy and, if needed, for 48 hours after the last dose of each cycle of chemotherapy. The initial dose is given 1-3 hours before chemotherapy is administered. The maximum daily dose is 6 mg given in divided doses three times a day.

  • How should I take Cesamet?

    Take Cesamet by mouth as prescribed by your doctor.

  • What should I avoid while taking Cesamet?

    Avoid potentially hazardous activities, such as driving or operating heavy machinery while taking Cesamet.

    Do not take Cesamet with alcohol, sedatives or sleep medicines, or other drugs that affect the functioning of your brain.

  • What are possible food and drug interactions associated with Cesamet?

    If Cesamet is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Cesamet with the following: alcohol, anticholinergics (such as atropine, scopolamine), antihistamines (such as loratadine), antipyrine, central nervous system (CNS) depressants (such as buspirone, codeine, diazepam, ethanol, lithium, lorazepam, muscle relaxants, phenobarbital, secobarbital), certain antidepressants (such as amitriptyline, amoxapine, desipramine), disulfiram, fluoxetine, naltrexone, sedatives, sympathomimetics (such as amphetamines, cocaine), and theophylline.

  • What are the possible side effects of Cesamet?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: change in appetite, difficulty concentrating, dizziness/spinning feeling, drowsiness, dry mouth, euphoria (feeling "high"), headache, poor coordination, trouble sleeping, weakness

  • Can I receive Cesamet if I am pregnant or breastfeeding?

    The effects of Cesamet during pregnancy and breastfeeding are unknown. Cesamet is not recommended during breastfeeding. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Cesamet?

    If you miss a dose of Cesamet, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store Cesamet?

    Store at room temperature.