Chlorpropamide

Generic Name: Chlorpropamide

  • What is this medication and its most common uses?

    Chlorpropamide is a medicine used along with diet and exercise to help control high blood sugar in adults with type 2 diabetes.

  • What should I know when beginning and continuing on this medication?

    How does this medication work?

    Chlorpropamide helps your body release more insulin, thereby helping to control your blood sugar.

    What are the beneficial effects of this medication and when should I begin to have results?

    What: Lowering your blood sugar to a normal level may prevent or delay potential complications associated with diabetes, such as blindness, kidney failure, or heart problems.

    When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you take chlorpropamide exactly as your healthcare provider has prescribed.

    How do I know it is working?

    Check your blood sugar regularly and as per your healthcare provider's recommendations. Your healthcare provider will also do regular blood tests to measure your blood sugar levels and your hemoglobin A1C (which estimates your average blood sugar levels over a 2- to 3-month period). Stay on your prescribed diet and exercise program, as this will also affect the results of your blood tests.

  • What are the possible side effects of this medication?

    The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

    More common side effects may include: stomach problems (such as nausea).

    Less common side effects may include:

    Low blood sugar with symptoms such as shaking, sweating, rapid heartbeat, changes in your vision, hunger, headache, or changes in your mood. Your risk of low blood sugar is higher if you do not eat enough, drink alcohol, or take other medicines to lower your blood sugar.

    Increased risk of life-threatening heart problems.

  • Who should not take this medication?

    Do not take chlorpropamide if you are allergic to it or to any of its ingredients.

  • What should I tell my healthcare provider before I take the first dose of this medication?

    Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with chlorpropamide. Also, talk to your healthcare provider about your complete medical history, especially if you have a condition known as glucose-6-phosphate dehydrogenase (G6PD) deficiency; heart, kidney, or liver problems; or if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

    Adults: The usual starting dose is 250 milligrams once a day. Your healthcare provider may adjust your dose as needed, until the desired effect is achieved.

    If you are elderly or have kidney or liver impairment, your healthcare provider may adjust your dose appropriately.

    If you are also using insulin, your healthcare provider may adjust the dose of your insulin.

  • How should I take this medication?

    Take chlorpropamide exactly as prescribed by your healthcare provider. Do not change your dose or stop taking chlorpropamide without first talking to your healthcare provider.

    Take chlorpropamide once a day in the morning with breakfast.

    If your body is under some types of stress (such as a fever, infection, trauma [such as a car accident], or surgery), your healthcare provider may need to adjust the dose of your diabetes medicine.

    While you are taking chlorpropamide, stay on your diet and exercise program, and check your blood sugar regularly as directed by your healthcare provider.

  • What should I avoid while taking this medication?

    Do not drive, operate heavy machinery, or engage in other tasks that require alertness until you know how chlorpropamide affects you.

  • What are the possible food and drug interactions associated with this medication?

    If chlorpropamide is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Chlorpropamide may interact with numerous medications. Therefore, it is very important that you tell your healthcare provider about any other medications you are taking.

  • May I receive this medication if I am pregnant or breastfeeding?

    The effects of chlorpropamide during pregnancy are unknown. Chlorpropamide can be found in your breast milk if you take it while breastfeeding. Do not breastfeed while you are taking chlorpropamide. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of this medication?

    If you miss a dose of chlorpropamide, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store this medication?

    Store at room temperature. Protect from light.