Cimzia

Generic Name: Certolizumab pegol

  • What is Cimzia?

    Cimzia is a medication known as a tumor necrosis factor (TNF) blocker. It is used in adults to reduce the symptoms of moderately to severely active Crohn's disease.
  • What is the most important information I should know about Cimzia?

    Cimzia is a medicine that affects your immune system; it may lower the ability of your immune system to fight infections. Serious infections, including tuberculosis (TB), have occurred in people taking Cimzia. Some people have died from these infections. Your doctor should test you for TB before starting Cimzia. Your doctor should monitor you closely for signs and symptoms of TB during treatment with Cimzia.
  • Who should not take Cimzia?

    Do not take Cimzia if you are allergic to any of its ingredients. This drug should be avoided if you have tuberculosis, hepatitis B, or cancer, or if you are scheduled to receive a vaccine.
  • What should I tell my doctor before I take the first dose of Cimzia?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Cimzia. Also talk to your doctor about your complete medical history, especially if you have an infection or signs of an infection (such as open sores, fever, cough, or flu-like symptoms), cancer, hepatitis B, HIV, diabetes, seizure disorder, any disease that affects your nervous system, or heart failure. Also tell the doctor if you are scheduled to receive a vaccine.
  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval

    Adults: The initial dose is 400 milligrams (mg) given as 2 injections, with the same dose given again at weeks 2 and 4. The maintenance dose is 400 mg every 4 weeks.

  • How should I take Cimzia?

    Cimzia should be injected by your healthcare provider. Each dose of Cimzia will be given as 2 separate injections under the skin in your stomach area (abdomen) or upper thigh.
  • What should I avoid while taking Cimzia?

    Avoid receiving any vaccines while you are being treated with Cimzia.
  • What are possible food and drug interactions associated with Cimzia?

    If Cimzia is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before receiving a vaccine or taking Kineret (anakinra), since this may increase the risk of serious infections.
  • What are the possible side effects of Cimzia?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Common side effects may include: upper respiratory infections, urinary tract infections, joint pain

    Serious and possibly life-threatening side effect may include: serious infections including tuberculosis, cancer including lymphoma, blood problems (decrease in blood cells that help fight infections or stop bleeding), heart failure, immune system reactions including a lupus-like syndrome (symptoms of this include shortness of breath, joint pain, rash on the cheeks and arms that worsen with sun exposure)

    If you experience severe allergic reactions, such as hives, difficulty breathing, and swelling of the throat, seek immediate medical attention.

  • Can I receive Cimzia if I am pregnant or breastfeeding?

    Cimzia should be avoided during pregnancy and breastfeeding. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
  • What should I do if I miss a dose of Cimzia?

    Ask your doctor for advice.
  • How should I store Cimzia?

    Cimzia should be refrigerated but not frozen.