What is Cisplatin?Cisplatin is a medicine used in combination with other anticancer medications to treat testicular or ovarian cancer that has spread to other parts of your body. It is also used to treat certain types of bladder cancer that cannot be treated with surgery or radiotherapy. Cisplatin is administered intravenously (through a vein in your arm).
What is the most important information I should know about Cisplatin?Cisplatin can cause kidney damage, myelosuppression (a decrease in the production of blood cells), loss of motor function, or ototoxicity (damage to the hearing or balance functions of your ear). Your doctor will regularly monitor your blood counts, kidney and liver function, nerve function, and hearing.
Cisplatin can cause an imbalance of your electrolytes (chemicals that are important for the cells in your body to function, such as sodium and potassium).
Cisplatin can cause severe allergic reactions. Tell your doctor immediately if you experience facial swelling, wheezing, fast heart rate, or low blood pressure. Your doctor will monitor you for allergic reactions.
Cisplatin can cause high uric acid levels in your blood.
Severe nausea and vomiting can occur with cisplatin treatment. Your doctor may prescribe for you a medicine to take on the day of cisplatin therapy to help prevent nausea and vomiting.
Who should not take Cisplatin?Your doctor will not administer cisplatin to you if you are allergic to it, any of its ingredients, or to platinum-containing medications. Also, your doctor will not administer cisplatin to you if you have kidney problems, myelosuppression, or hearing impairment.
What should I tell my doctor before I take the first dose of Cisplatin?Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with cisplatin. Also, talk to your doctor about your complete medical history, especially if you have a history of kidney disease, eye or vision problems, gout (severe and painful inflammation of the joints), hearing impairment, nerve problems, or are pregnant, plan to become pregnant, or are breastfeeding.
What is the usual dosage?The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.
Adults: Your doctor will prescribe and administer the appropriate dose for you based on your weight and the type of cancer being treated.
How should I take Cisplatin?Your doctor will administer cisplatin to you.
What should I avoid while taking Cisplatin?Do not miss your scheduled follow-up appointments with your doctor.
Do not become pregnant while on cisplatin therapy.
What are possible food and drug interactions associated with Cisplatin?If cisplatin is used with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to tell your doctor if you are taking any of the following prior to treatment with cisplatin: antiseizure medications (such as gabapentin or valproic acid) and pyridoxine.
What are the possible side effects of Cisplatin?Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.
Side effects may include: allergic reactions, blood disorders, dehydration, electrolyte imbalance, facial swelling, hearing impairment, heart problems, hiccups, increased heartbeat, kidney damage, loss of taste, low blood pressure, muscle cramps or pain, nausea, rash, seizures, vomiting, weakness, wheezing
Can I receive Cisplatin if I am pregnant or breastfeeding?Cisplatin may cause harm to your unborn baby if received during pregnancy. Cisplatin can be found in your breast milk if you receive it while breastfeeding. Do not breastfeed while you are receiving cisplatin. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
What should I do if I miss a dose of Cisplatin?Do not miss your scheduled follow-up appointments with your doctor.
How should I store Cisplatin?Your doctor will store this medication for you.