Clobetasol Propionate Cream

Generic Name: Clobetasol

  • What is Clobetasol Propionate Cream?

    Clobetasol propionate cream is a topical medicine (applied to the skin surface) that is used for the relief of inflammation and itching of the skin.

  • What is the most important information I should know about Clobetasol Propionate Cream?

    Clobetasol propionate is for external use only. Do not use it in your eyes, face, underarms, vagina, or groin areas.

    Clobetasol propionate can have a greater effect on children because they are more likely to absorb large amounts of the medicine through the skin. Long-term use can affect the growth and development of children. Talk to your doctor if you think your child is not growing at a normal rate after using this medication for a long period of time.

    Do not use clobetasol propionate for any other condition other than that which your doctor has prescribed.

    Contact your doctor if you notice irritation or any skin reactions in the area being treated or if your condition does not improve within two weeks of treatment.

  • Who should not take Clobetasol Propionate Cream?

    Do not use clobetasol propionate if you are allergic to it, any of its ingredients, or to similar products.

  • What should I tell my doctor before I take the first dose of Clobetasol Propionate Cream?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with clobetasol propionate. Also, talk to your doctor about your complete medical history, especially if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.


    Adults and children ≥12 years: Apply a thin film to the affected area(s) twice a day.

    Limit the treatment to 2 consecutive weeks, and do not use more than 50 grams (g) a week.

  • How should I take Clobetasol Propionate Cream?

    Apply clobetasol propionate exactly as prescribed by your doctor. Do not apply extra doses or apply more often without asking your doctor.

    Rub the cream into skin gently and completely.

  • What should I avoid while taking Clobetasol Propionate Cream?

    Do not use clobetasol propionate in your eyes, face, underarms, or groin areas.

    Do not bandage, cover, or wrap the treated skin area as to be occlusive.

  • What are possible food and drug interactions associated with Clobetasol Propionate Cream?

    No significant interactions have been reported with clobetasol propionate at this time. However, always tell your doctor about any medicines you take, including over-the-counter medications, vitamins, and herbal supplements.

  • What are the possible side effects of Clobetasol Propionate Cream?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: acne (pimples), burning, cracking of the skin, dermatitis (inflammation of the skin), infection, irritation, itching, numbness of the fingers, redness, stinging, sweat rash, telangiectasia (widely open blood vessels in the outer layer of the skin)

  • Can I receive Clobetasol Propionate Cream if I am pregnant or breastfeeding?

    The effects of clobetasol propionate during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Clobetasol Propionate Cream?

    If you miss a dose of clobetasol propionate, apply it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not apply two doses at once.

  • How should I store Clobetasol Propionate Cream?

    Store at room temperature. Do not refrigerate.