Generic Name: Clomiphene

  • What is Clomid?

    Clomid is prescribed for the treatment of ovulatory dysfunction in women who want to become pregnant.

  • What is the most important information I should know about Clomid?

    Properly timed sexual intercourse is very important to increase the chances of conception. The likelihood of conception diminishes with each succeeding course of treatment. Your doctor will determine the need for continuing therapy after the first course.

    Your doctor will evaluate you for normal liver function and normal estrogen levels before considering you for treatment with Clomid.

    Your doctor will also examine you for pregnancy, ovarian enlargement, or cyst formation prior to treatment with this drug and between each treatment cycle. He or she will do a complete pelvic examination before each course of this medication.

    Clomid treatment increases the possibility of multiple births; also, birth defects have been reported following treatment with Clomid, although no direct effects of the drug on the unborn child have been established.

    Ovarian hyperstimulation syndrome (or OHSS, enlargement of the ovary) has occurred in women receiving treatment with Clomid. OHSS may progress rapidly and become serious. The early warning signs are severe pelvic pain, nausea, vomiting, and weight gain. Symptoms include abdominal pain, abdominal enlargement, nausea, vomiting, diarrhea, weight gain, difficult or labored breathing, and less urine production. If you experience any of these warning signs or symptoms, notify your doctor immediately.

    To lessen the risks associated with abnormal ovarian enlargement during treatment with Clomid, the lowest effective dose should be prescribed. Women with polycystic ovarian syndrome may be unusually sensitive to certain hormones and may respond abnormally to usual doses of this drug. If you experience pelvic pain, notify your doctor, who may discontinue your use of Clomid until the ovaries return to pretreatment size.

    The safety of long-term treatment with Clomid has not been established. Prolonged use may increase the risk of a tumor in the ovaries.

  • Who should not take Clomid?

    If you are pregnant or think you may be, do not take this drug.

    Unless directed to do so by your doctor, do not use this medication if you have an uncontrolled thyroid or adrenal gland disorder, an abnormality of the brain such as a pituitary gland tumor, liver disease or a history of liver problems, abnormal uterine bleeding of undetermined origin, ovarian cysts, or enlargement of the ovaries not caused by polycystic ovarian syndrome (a hormonal disorder causing lack of ovulation).

    Do not take this medication if you are allergic to Clomid or to any of its ingredients.

  • What should I tell my doctor before I take the first dose of Clomid?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with this drug. Also, talk to your doctor about your complete medical history.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: The recommended dosage for the first course of treatment is 50 milligrams (mg) daily for 5 days. The dose may be increased to 100 mg for 5 days only in women who do not ovulate in response to 50 mg of Clomid.

  • How should I take Clomid?

    Take this medication exactly as prescribed by your doctor.

  • What should I avoid while taking Clomid?

    Because blurred vision and other visual symptoms may occur occasionally with Clomid treatment, be cautious about driving a car or operating dangerous machinery, especially under conditions of variable lighting. If you experience visual disturbances, notify your doctor immediately. Symptoms of visual disturbance may include blurring, spots or flashes, double vision, intolerance to light, decreased visual sharpness, loss of peripheral vision, and distortion of space. Your doctor may recommend a complete evaluation by an eye specialist.

  • What are possible food and drug interactions associated with Clomid?

    No significant interactions have been reported with Clomid at this time. However, always tell your doctor about any medications you take, including over-the-counter drugs, vitamins, and herbal supplements.

  • What are the possible side effects of Clomid?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: abdominal discomfort, enlargement of the ovaries, hot flushes, nausea and vomiting, breast discomfort, visual symptoms, headaches, abnormal uterine bleeding

  • Can I receive Clomid if I am pregnant or breastfeeding?

    If you become pregnant, notify your doctor immediately. You should not be taking this drug while you are pregnant. This drug should be used with caution in breastfeeding women.

  • What should I do if I miss a dose of Clomid?

    Take it as soon as you remember. If it is time for your next dose, take the two doses together and go back to your regular schedule. If you miss more than one dose, contact your doctor.

  • How should I store Clomid?

    Store at room temperature in a tightly closed container, away from light, moisture, and excessive heat.

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I'm Kristen Dore, PharmD. Welcome to PDR Health!

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