Generic Name: Chlorthalidone

  • What is Clorpres?

    Clorpres is a combination medicine used to treat high blood pressure. Clorpres contains two medicines: clonidine (a medicine that lowers your blood pressure) and hydrochlorothiazide, a diuretic (water pill).

  • What is the most important information I should know about Clorpres?

    Do not abruptly stop taking Clorpres without first consulting your doctor. Sudden discontinuation of Clorpres can lead to rapid rise in blood pressure, nervousness, agitation, or headache.

    If you have asthma or a history of allergies, you may be at risk for an allergic reaction to Clorpres.

    Clorpres can cause a decrease in your blood potassium levels. Contact your doctor if you experience excessive thirst, tiredness, restlessness, muscle pain or cramps, or increased heart rate.

  • Who should not take Clorpres?

    Do not take Clorpres if you are allergic to it or any of its ingredients. Also, do not take Clorpres if you are allergic to sulfonamide medications (such as sulfamethoxazole).

    Do not take Clorpres if you are unable to urinate.

  • What should I tell my doctor before I take the first dose of Clorpres?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Clorpres. Also, talk to your doctor about your complete medical history, especially if you have asthma, kidney or liver disease, gout (severe and painful inflammation of the joints), systemic lupus erythematosus (disease that effects the immune system), diabetes, heart disease, thyroid disorders, had a stroke, or have recently had a heart attack, are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: Your doctor will prescribe the appropriate dose for you based on your previous blood pressure medication.

  • How should I take Clorpres?

    Take Clorpres exactly as prescribed by your doctor. You can take it once or twice a day.

  • What should I avoid while taking Clorpres?

    Do not stop taking Clorpres suddenly. Your doctor will gradually reduce your dose over several days to avoid withdrawal symptoms.

    Do not drive or operate dangerous machinery until you know how Clorpres affects you, as this medication can cause drowsiness.

    Do not consume alcohol or other medications that can cause drowsiness.

  • What are possible food and drug interactions associated with Clorpres?

    If Clorpres is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Clorpres with the following: alcohol, barbiturates (such as phenobarbital), certain antidepressants (such as amitriptyline), insulin, lithium, oral diabetes medications, sedatives (such as diazepam), or tubocurarine.

  • What are the possible side effects of Clorpres?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: constipation, dizziness, drowsiness, dry mouth, sedation

  • Can I receive Clorpres if I am pregnant or breastfeeding?

    The effects of Clorpres during pregnancy are unkown. Clorpres is found in breast milk; do not use it if you are breastfeeding. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Clorpres?

    If you miss a dose of Clorpres, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store Clorpres?

    Store at room temperature.