Collagenase Santyl

Generic Name: Collagenase

  • What is Collagenase Santyl?

    Collagenase Santyl is a topical ointment (applied directly on the skin) used for debriding long-term skin ulcers or severely burned areas. Collagenase Santyl removes unhealthy tissue from your wound.

  • What is the most important information I should know about Collagenase Santyl?

    Collagenase Santyl can be affected by certain detergents or skin disinfectants containing heavy metal ions (such as mercury or silver). It can also be affected by soaks, especially if it contains metal ions or acidic solutions. If you suspect the use of such materials, carefully cleanse the area by repeated washings with normal saline. Certain cleansing agents (such as Dakin's solution) or normal saline can be used with Collagenase Santyl.

    Collagenase Santyl can increase the risk of infections of your blood. Tell your doctor if you feel abnormally weak or ill. Your doctor will closely monitor you for bacterial infections.

    Collagenase Santyl can cause a slight temporary reddening of the surrounding area(s) of the affected area(s), especially when you apply this medicine out of the area of your wound.

  • Who should not take Collagenase Santyl?

    Do not use Collagenase Santyl if you are allergic to it or any of its ingredients.

  • What should I tell my doctor before I take the first dose of Collagenase Santyl?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Collagenase Santyl. Also, talk to your doctor about your complete medical history.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: Apply to the affected area(s) once a day or more frequently if the dressing becomes soiled.

  • How should I take Collagenase Santyl?

    Apply Collagenase Santyl exactly as prescribed by your doctor. The affected area should be cleansed and rinsed before applying this medicine. Apply Collagenase Santyl directly to the wound or to a sterile gauze pad, which is then applied to the wound.

  • What should I avoid while taking Collagenase Santyl?

    Do not use Collagenase Santyl with certain detergents or soaks, especially if they contain mercury, silver, or acidic solutions.

  • What are possible food and drug interactions associated with Collagenase Santyl?

    If Collagenase Santyl is used with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Collagenase Santyl with the following: certain detergents or skin disinfectants containing heavy metal ions or soaks containing metal ions or acidic solutions.

  • What are the possible side effects of Collagenase Santyl?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: allergic reactions

  • Can I receive Collagenase Santyl if I am pregnant or breastfeeding?

    The effects of Collagenase Santyl during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Collagenase Santyl?

    If you miss a dose of Collagenase Santyl, apply it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not apply two doses at once.

  • How should I store Collagenase Santyl?

    Store at room temperature.