Generic Name: Hydrocortisone

  • What is this medication and its most common uses?

    Colocort is a medicine used in combination with other medicines to treat ulcerative colitis (an inflammatory disease of the large intestine). Colocort is available as an enema.

  • What should I know when beginning and continuing on this medication?

    How does this medication work?

    Colocort works by reducing swelling in the colon.

    What are the beneficial effects of this medication and when should I begin to have results?

    What: Colocort may improve symptoms of ulcerative colitis, such as decreased diarrhea and bleeding, weight gain, improved appetite, and decreased fever.

    When: Colocort may start to improve your symptoms within 3 to 5 days.

    How do I know it is working?

    You may feel an improvement in your symptoms once you begin using Colocort. Your healthcare provider may also order tests regularly to check how well your condition is controlled.

  • What are the possible side effects of this medication?

    The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

    More common side effects may include: pain or burning in the treated area, rectal bleeding.

    Less common side effects may include:

    Eye problems, such as glaucoma (high pressure in the eye), cataracts, or an infection.

    Adrenal insufficiency (a disorder where the body does not make enough of certain hormones), with symptoms such as tiredness that worsens and does not go away, nausea or vomiting, dizziness or fainting, muscle weakness, irritability and depression, loss of appetite, or weight loss.

    Colocort may also cause increased blood pressure, salt and water retention in your body, decreased blood potassium levels, or increase your risk of developing an infection.

  • Who should not take this medication?

    Do not use Colocort if you are allergic to it or any of its ingredients.

    Do not use Colocort if you have certain infections.

    Do not use Colocort right before or after you have an intestinal surgery called an ileocolostomy.

  • What should I tell my healthcare provider before I take the first dose of this medication?

    Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Colocort. Also, talk to your healthcare provider about your complete medical history, especially if you have kidney or thyroid problems, cirrhosis (scarring of the liver), high blood pressure, any type of infection (including tuberculosis [a bacterial infection that affects the lungs] or an eye infection), recently have been in contact with anyone who has chickenpox or measles, stomach or intestinal problems (such as an ulcer or diverticulitis [inflammation in the large intestines that results in pouches]), psychiatric conditions (such as mood swings or personality changes), osteoporosis (thin, weak bones), myasthenia gravis (a disease characterized by long-lasting fatigue and muscle weakness), take a medicine called aspirin, or if you plan to have surgery.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

    Adults: Use one enema every night for 21 days, or as directed by your healthcare provider.

  • How should I take this medication?

    Use Colocort exactly as prescribed by your healthcare provider. Do not use it more often or stop using it without first talking to your healthcare provider.

    Shake the bottle well before using it.

    Please review the instructions that came with your prescription on how to properly apply Colocort.

    If you do not see an improvement in your condition in 2 or 3 weeks, call your healthcare provider.

  • What should I avoid while taking this medication?

    Do not come in contact with anyone who has chickenpox or measles while you are using Colocort.

    Do not receive certain vaccines during treatment with Colocort without first talking to your healthcare provider.

  • What are the possible food and drug interactions associated with this medication?

    No significant interactions have been reported with Colocort at this time. However, always tell your healthcare provider about any medicines you take, including over-the-counter medications, vitamins, and herbal supplements.

  • May I receive this medication if I am pregnant or breastfeeding?

    The effects of Colocort during pregnancy and breastfeeding are unknown. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of this medication?

    If you miss a dose of Colocort, apply it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not apply two doses at once.

  • How should I store this medication?

    Store at room temperature.