Coreg
Generic Name: Carvedilol
What is Coreg?
Coreg is used, often with other medications, to treat high blood pressure. It is also used to treat patients who had a heart attack that reduced how well the heart pumps (left ventricular dysfunction, or LVD), and to treat patients with certain types of heart failure.What is the most important information I should know about Coreg?
If you are taking Coreg, do not suddenly stop taking it, as this may lead to chest pain and, in some cases, heart attack. If your doctor decides that you should stop taking Coreg, he or she will slowly reduce your dose over a period of time before stopping it completely.Coreg can cause a drop in blood pressure when you first stand up, resulting in dizziness or even fainting. If this happens, sit or lie down and notify your doctor. Taking the drug with food reduces the chance of this problem. During the first month of therapy and after a change in your dose, use caution when driving or operating dangerous machinery.
Coreg may hide the symptoms of low blood sugar. Monitor blood sugar levels and report any changes to your doctor.
Rarely, Coreg leads to worsened kidney function in heart failure patients, so your kidney function should be monitored if your doctor increases your dose of Coreg.
If you experience symptoms of heart failure, such as weight gain and shortness of breath, contact your doctor immediately.
Who should not take Coreg?
Do not use Coreg if you have breathing problems, certain serious heart conditions (such as a slow or irregular heartbeat), or liver disease.Do not take Coreg if you are allergic to it or any of its ingredients.
What should I tell my doctor before I take the first dose of Coreg?
Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Coreg. Also, talk to your doctor about your complete medical history, especially if you have lung problems, high blood sugar, thyroid problems, liver disease, problems with blood flow to the feet/legs, pheochromocytoma (a rare tumor that develops in the adrenal gland), or are scheduled for surgery involving anesthetics. Also, tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding.What is the usual dosage?
The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.Dosage must be individualized and closely monitored by your doctor.
Blood Pressure
Adults: The recommended starting dose is 6.25 milligrams (mg) twice a day. If needed, your dose can be increased to 12.5 mg twice a day after 1-2 weeks. Your dose can be increased to 25 mg twice a day after another 1-2 weeks. Your total daily dose should not exceed 50 mg.
Heart Failure
Adults: The recommended starting dose of Coreg is 3.125 mg twice a day for 2 weeks. If needed, your dose may be increased to 6.25, 12.5, or up to 25 mg two times a day, with each dose increase occurring at 2-week intervals. The maximum dose, for people weighing >187 pounds, is 50 mg twice a day.
Left Ventricular Dysfunction Following a Heart Attack
Adults: The recommended starting dose is 6.25 mg twice a day and may be increased after 3-10 days, if needed, to 12.5 mg twice a day, then again to the maximum dose of 25 mg twice a day. A lower starting dose may be used if necessary.
How should I take Coreg?
Take Coreg with food.What should I avoid while taking Coreg?
Do not interrupt or discontinue using Coreg without speaking to your doctor. Abrupt discontinuation can lead to worsening of your symptoms.Avoid driving or hazardous tasks until you know how Coreg affects you.
What are possible food and drug interactions associated with Coreg?
If Coreg is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Coreg with any of the following: calcium channel blockers (such as diltiazem or verapamil), cimetidine, clonidine, cyclosporine, diabetes medications (such as insulin), digoxin, fluoxetine, MAO inhibitors (including the antidepressants phenelzine and tranylcypromine), paroxetine, propafenone, quinidine, reserpine, and rifampin.What are the possible side effects of Coreg?
Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.Side effects may include: anemia, back pain, bronchitis (inflammation of the air passages within the lungs), cough, diarrhea, dizziness, dry eyes, fainting, fatigue, fluid in the lungs, headache, increased blood sugar levels, increased cholesterol, joint pain, low blood pressure, nausea, pain, shortness of breath, sinus problems, slow heartbeat, swelling, upper respiratory infection, vision changes, vomiting, weakness, weight gain, wheezing
Can I receive Coreg if I am pregnant or breastfeeding?
The effects of Coreg during pregnancy and breastfeeding are unknown. Talk with your doctor before taking this drug if you are pregnant, plan to become pregnant, or are breastfeeding.What should I do if I miss a dose of Coreg?
Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take two doses at once.How should I store Coreg?
Store at room temperature away from light and moisture.
I'm Beth Isaac, PharmD. Welcome to PDR Health!
