Coreg CR

Generic Name: Carvedilol

  • What is this medication and its most common uses?

    Coreg CR is a medicine known as a beta-blocker, which is used alone or in combination with other medicines to treat high blood pressure. Coreg CR is also used for heart failure and after a heart attack that worsens how well the heart pumps.

  • What should I know when beginning and continuing on this medication?

    How does this medication work?

    Coreg CR is an extended release medicine (a type of capsule that releases medicine into your body throughout the day). It works by decreasing your heart rate, and relaxing and widening your blood vessels, allowing your blood to flow through with less resistance. This helps to lower your blood pressure.

    What are the beneficial effects of this medication and when should I begin to have results?


    High Blood Pressure: By lowering your blood pressure, Coreg CR may lower your risk of a stroke or a heart attack. Also, since Coreg CR is an extended-release medicine, you only need to take it once a day, which may make it easier for you to remember to take your medicine.

    Heart Failure: Coreg CR has been shown to reduce the worsening of heart failure and reduce the chance of death from heart failure.

    After a Heart Attack: Coreg CR has been shown to reduce the chance of death after a heart attack in people who have certain types of heart problems.

    When: Coreg CR may start lowering your blood pressure within 1 to 2 weeks. Though you may not feel an improvement or change in the way you feel, it is very important to keep taking your medicine as prescribed to keep your condition under control.

    How do I know it is working?

    Check your blood pressure regularly. Your healthcare provider will also check your blood pressure at every visit. Following an appropriate diet and exercise plan will also affect your blood pressure results.

  • What are the possible side effects of this medication?

    The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

    High Blood Pressure

    More common side effects may include: dizziness.

    Heart Failure and After a Heart Attack

    More common side effects may include: dizziness, fatigue, low blood pressure, diarrhea, high blood sugar, weakness, slow heartbeat, weight gain.

    Less common side effects of Coreg CR may include:

    Breathing problems or worsened heart failure with symptoms such as weight gain, increased shortness of breath, or a slow heartbeat.

    Coreg CR may hide symptoms of low blood sugar levels if you have diabetes.

  • Who should not take this medication?

    Do not take Coreg CR if you are allergic to it or any of its ingredients.

    Do not take Coreg CR if you have certain heart problems (such as heart failure, a slow heartbeat, or your heart skips a beat).

    Do not take Coreg CR if you have asthma or other breathing problems.

    Do not take Coreg CR if you have severe liver disease.

  • What should I tell my healthcare provider before I take the first dose of this medication?

    Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Coreg CR. Also, talk to your healthcare provider about your complete medical history, especially if you have lung problems (such as bronchitis or emphysema); problems with blood flow in your feet and legs; diabetes; pheochromocytoma (tumor of the adrenal gland); liver, kidney, or thyroid problems; or if you are scheduled for surgery (including cataract surgery).

    Tell your healthcare provider if you have a history of severe allergic reactions to any allergens, because Coreg CR may decrease the effectiveness of epinephrine, a medicine used to treat such reactions.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

    High Blood Pressure and After a Heart Attack

    Adults: The recommended starting dose is 20 milligrams (mg) once a day. Your healthcare provider may increase your dose as needed until the desired effect is achieved.

    Heart Failure

    Adults: The recommended starting dose is 10 mg once a day. Your healthcare provider may increase your dose as appropriate.

    It is important that you do not stop taking this medication abruptly. If you need to change or stop taking this medication, it is important that you only do this with the guidance of your healthcare provider.

  • How should I take this medication?

    Take Coreg CR exactly as prescribed by your healthcare provider. Do not change your dose or stop taking Coreg CR without first talking to your healthcare provider.

    Take Coreg CR with food.

    Swallow Coreg CR capsules whole. Do not break, crush, or chew them.

    If you have trouble swallowing Coreg CR whole, you may carefully open the capsule and sprinkle the beads over a spoonful of applesauce, and eat it right away. The applesauce should not be warm. Do not sprinkle the beads on any foods other than applesauce.

  • What should I avoid while taking this medication?

    Do not drive a car, operate machinery, or engage in other tasks requiring alertness until you know how Coreg CR affects you.

  • What are the possible food and drug interactions associated with this medication?

    If Coreg CR is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Coreg CR with any of the following: amiodarone, antidepressant medications known as monoamine oxidase inhibitors (MAOIs) (such as phenelzine or tranylcypromine), blood pressure/heart medications known as calcium channel blockers (such as diltiazem or verapamil), clonidine, cyclosporine, diabetes medicines (such as insulin), digoxin, fluconazole, fluoxetine, paroxetine, propafenone, quinidine, reserpine, or rifampin.

  • May I receive this medication if I am pregnant or breastfeeding?

    The effects of Coreg CR during pregnancy and breastfeeding are unknown. Do not breastfeed while you are taking Coreg CR. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of this medication?

    If you miss a dose of Coreg CR, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store this medication?

    Store at room temperature.

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