What is Corzide?Corzide is a combination medication of nadolol and bendroflumethiazide used to treat high blood pressure.
What is the most important information I should know about Corzide?Do not stop taking Corzide abruptly; this can cause increased chest pain and possibly a heart attack. If necessary, your doctor should slowly reduce your dose.
Corzide may hide the symptoms of low blood sugar or may alter blood sugar levels. If you have diabetes (high blood sugar), you should report any changes in your blood sugar levels to your doctor right away.
You must take Corzide regularly for it to be effective. Since blood pressure declines gradually, it may be several weeks before you get the full benefit of Corzide. You must continue taking it even if you are feeling well. Corzide does not cure high blood pressure; it only keeps it under control.
If you are going for surgery in the near future, Corzide should be slowly withdrawn several days before surgery.
Who should not take Corzide?Do not use Corzide if you have breathing problems, certain heartbeat irregularities, active heart failure, inability to urinate, diabetes, low blood sugar, or if you are sensitive to or have ever had an allergic reaction to Corzide, its ingredients, or similar drugs. Corzide should be administered with caution to patients with breathing problems, such as tightening of the airways or bronchospasm-related diseases.
What should I tell my doctor before I take the first dose of Corzide?Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Corzide. Also, talk to your doctor about your complete medical history, especially if you have breathing problems, high blood sugar, lung disease, a history of long-term heart failure, kidney disease, liver disease, allergic reactions, seasonal allergies, or thyroid problems.
What is the usual dosage?The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.
Adults: The usual dose is one 40/5 milligram (mg) tablet daily. If necessary, you may need one 80/5 mg tablet daily. If you have kidney problems, you may be prescribed a lower dose or take it less often. If Corzide fails to bring your blood pressure under control, your doctor may gradually add another high blood pressure medication.
How should I take Corzide?Corzide may be taken with or without food. Take it exactly as prescribed even if you do not have any symptoms.
What should I avoid while taking Corzide?Try not to miss any doses. Corzide should not be stopped suddenly.
Corzide may increase the effects of alcohol. Do not drink alcoholic beverages while taking Corzide.
What are possible food and drug interactions associated with Corzide?If Corzide is taken with any other drug, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Corzide with any of the following: alcohol, amphotericin B, antidepressant medications known as monoamine oxidase (MAO) inhibitors (such as phenelzine or tranylcypromine), antigout medications, barbiturates, blood pressure medications (such as chlorothiazide or enalapril), blood thinners, calcium salts, cholestyramine, colestipol, corticosteroids, diabetes medications, diazoxide, digoxin, epinephrine, lithium, methenamine, narcotics (such as morphine), and nonsteroidal anti-inflammatory medications (such as naproxen, reserpine, or sulfinpyrazone).
What are the possible side effects of Corzide?Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.
Side effects may include: breathing problems, changes in heartbeat, cold hands and feet, dizziness, fatigue, low blood pressure, low potassium levels
Can I receive Corzide if I am pregnant or breastfeeding?The effects of Corzide during pregnancy and breastfeeding are unknown. However, both active ingredients of Corzide, nadolol and bendroflumethiazide, are excreted in human milk, which may potentially cause a serious adverse reaction in nursing infants. Talk with your doctor before taking this drug if you are pregnant, plan to become pregnant, or are breastfeeding.
What should I do if I miss a dose of Corzide?Take it as soon as you remember. If it is within 8 hours of your next scheduled dose, skip the one you missed and go back to your regular schedule. Do not take two doses at once.
How should I store Corzide?Store at room temperature, away from heat, in a tightly closed container.
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