Generic Name: Dorzolamide

  • What is this medication and its most common uses?

    Cosopt is an eye drop used to lower pressure in the eye in people with open-angle glaucoma or high pressure in the eye. Cosopt contains two medicines: dorzolamide and timolol.

  • What should I know when beginning and continuing on this medication?

    How does this medication work?

    Increased pressure in the eye and glaucoma can result when the fluid that flows through and nourishes the lens and cornea (the clear front part of the eye) cannot drain normally. Cosopt is thought to lower pressure in your eye by reducing the production of this fluid.

    What are the beneficial effects of this medication and when should I begin to have results?

    What: By reducing the pressure in your eye, Cosopt may help reduce the risk of developing glaucoma-related vision loss and nerve damage.

    When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you use Cosopt exactly as your healthcare provider has prescribed.

    How do I know it is working?

    Your healthcare provider may examine your eyes or perform certain tests to check how well this medication is working.

  • What are the possible side effects of this medication?

    The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

    More common side effects may include: bitter, sour, or unusual taste; burning or stinging in your eye.

    Less common side effects may include:

    Serious allergic reactions, with symptoms such as skin rash, sore throat, fever, joint pain, cough, shortness of breath, paleness, or yellowing of your skin or the whites of your eyes.

    Cosopt may cause muscle weakness, breathing problems, or heart failure (with symptoms such as weight gain, increased shortness of breath, or a slow heartbeat).

    Cosopt may hide symptoms of low blood sugar levels if you have diabetes.

  • Who should not take this medication?

    Do not use Cosopt if you are allergic to it or to any of its ingredients.

    Do not use Cosopt if you have certain heart problems (such as heart failure, a slow heartbeat, or if your heart skips a beat).

    Do not use Cosopt if you have or had breathing problems such as asthma or chronic obstructive pulmonary disease (COPD) (narrowing of the lungs that makes it hard to breathe).

  • What should I tell my healthcare provider before I take the first dose of this medication?

    Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Cosopt. Also, talk to your healthcare provider about your complete medical history, especially if you have heart, thyroid, kidney, liver, or breathing problems; diabetes; blood circulation problems; eye problems (including an infection or surgery); myasthenia gravis (a disease characterized by long-lasting fatigue and muscle weakness); if you are scheduled for surgery; or if you are pregnant, plan to become pregnant, or are breastfeeding.

    Tell your healthcare provider if you have a history of severe allergic reactions to any allergens, because Cosopt may decrease the effectiveness of epinephrine, a medicine used to treat such reactions.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

    Adults and children ≥2 years: Apply 1 drop into the affected eye(s) twice a day (one drop in the morning and one drop in the evening).

  • How should I take this medication?

    Use Cosopt exactly as prescribed by your healthcare provider. Do not change your dose or stop using Cosopt without first talking to your healthcare provider.

    Cosopt contains a preservative that may be absorbed by your contact lenses. Remove your contact lenses prior to the administration of Cosopt. You may reinsert your contact lenses 15 minutes after you apply Cosopt.

    If you are using Cosopt with another eye drop, the drops should be applied at least 10 minutes apart.

    Please review the instructions that came with your prescription on how to properly use your eye drops.

  • What should I avoid while taking this medication?

    Do not allow the tip of the bottle to touch your eye or any other surface, as this can contaminate Cosopt.

  • What are the possible food and drug interactions associated with this medication?

    If Cosopt is used with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Cosopt with the following: acetazolamide, aspirin, blood pressure/heart medications known as beta-blockers (such as atenolol or propranolol) and calcium channel blockers (such as amlodipine or diltiazem), certain antidepressant medications known as selective serotonin reuptake inhibitors (SSRIs) (such as fluoxetine or sertraline), clonidine, digoxin, methazolamide, quinidine, or reserpine.

  • May I receive this medication if I am pregnant or breastfeeding?

    The effects of Cosopt during pregnancy are unknown. Cosopt can be found in your breast milk if you use it while breastfeeding. Do not breastfeed while you are using Cosopt. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of this medication?

    If you miss a dose of Cosopt, apply it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not apply two doses at once.

  • How should I store this medication?

    Store at room temperature. Protect from light.

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I'm Kristen Dore, PharmD. Welcome to PDR Health!

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