Generic Name: Hydroxocobalamin

  • What is Cyanokit?

    Cyanokit is an emergency treatment (antidote) used to treat cyanide poisoning, which may occur as a result of smoke inhalation, breathing or swallowing cyanide, or coming in contact with cyanide.

  • What is the most important information I should know about Cyanokit?

    Cyanokit may cause skin redness that may last up to 2 weeks, and urine discoloration that may last for up to 5 weeks, after it is administered. It may also cause an acne-like rash that may appear 7-28 days following treatment; this rash usually goes away without any treatment.

  • Who should not take Cyanokit?

    Patients with known hypersensitivity to hydroxocobalamin or cyanocobalamin should not take this drug.

  • What should I tell my doctor before I take the first dose of Cyanokit?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Cyanokit. Also, talk to your doctor about your complete medical history.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Cyanokit is given through the vein over a 15-minute period by an emergency care provider. A second dose may be administered if needed.

  • How should I take Cyanokit?

    An emergency care provider will administer this medication.

  • What should I avoid while taking Cyanokit?

    Avoid sun exposure if your skin is red after receiving Cyanokit.

  • What are possible food and drug interactions associated with Cyanokit?

    No formal drug interaction studies have been conducted with Cyanokit.

  • What are the possible side effects of Cyanokit?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: allergic reactions, increased blood pressure, red skin and mucous membranes, swelling of the feet and ankles, irregular heart rate, fluid in the lungs

    Signs of severe allergic reactions may include hives, difficulty breathing, and swelling of the throat. If any of these events occur, seek immediate medical attention.

  • Can I receive Cyanokit if I am pregnant or breastfeeding?

    Cyanokit should be avoided during pregnancy and in nursing mothers. Talk to your doctor if you are pregnant, plan to become pregnant, or are nursing.

  • What should I do if I miss a dose of Cyanokit?

    An emergency care provider will administer Cyanokit.

  • How should I store Cyanokit?

    Your hospital or emergency care provider will store this medication.

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I'm Kristen Dore, PharmD. Welcome to PDR Health!

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