Generic Name: Acetaminophen

  • What is Darvocet-N?

    Darvocet-N is used for the relief of mild to moderate pain, with or without fever.

  • What is the most important information I should know about Darvocet-N?

    There is a serious risk of overdose associated with Darvocet-N, which may lead to death within the first hour of overdosing, especially in patients with a history of emotional disturbances or suicide attempts or those who also take sedatives, tranquilizers, muscle relaxants, antidepressants, or other CNS depressants. Do not take more than 6 tablets of Darvocet-N 100 or 12 tablets of Darvocet-N 50 in 1 day.

    Darvocet-N is a potential drug of abuse. Do not share this medication with others or take it in any way other than how your doctor prescribed it for you. Keep out of reach of children.

    Call your doctor right away if you experience any pain or side effects while taking Darvocet-N. Individualization of dosage is essential to make optimal use of this medication.

  • Who should not take Darvocet-N?

    Do not take Darvocet-N if you are suicidal or have a history of addiction.

    Do not take Darvocet-N if you are sensitive or allergic to propoxyphene or acetaminophen, if you have asthma or severe lung problems including decreased breathing capacity or high amounts of carbon dioxide in the blood, or if you have a blockage of the bowel.

  • What should I tell my doctor before I take the first dose of Darvocet-N?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Darvocet-N. Also, talk to your doctor about your complete medical history, especially if you have kidney or liver problems, if you use alcohol in excess, have lung problems, a history of head injury, or if you are suicidal or have a history of addiction. Also, tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: The usual dosage is 100 milligrams (mg) of propoxyphene napsylate and 650 mg of acetaminophen every 4 hours as needed for pain. Your doctor may prescribe a lower dose depending on your medical history. The maximum recommended dose of propoxyphene napsylate is 600 mg per day.

  • How should I take Darvocet-N?

    Follow your doctor's directions exactly. Do not increase the amount you take without your doctor's approval.

  • What should I avoid while taking Darvocet-N?

    You should limit your intake of alcohol while taking this medication. Use caution while driving a vehicle or using machinery until you know how the drug affects you, as Darvocet-N can make you sleepy. Do not take more of the drug than your doctor has prescribed.

    Do not adjust the dose or discontinue Darvocet-N without consulting your doctor. Contact your doctor if you feel that discontinuation of therapy is appropriate; your doctor can provide a dose schedule to accomplish a gradual discontinuation of the medication, if necessary.

  • What are possible food and drug interactions associated with Darvocet-N?

    If Darvocet-N is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Darvocet-N with the following: alcohol, amiodarone, anticonvulsants, antidepressants, especially those that are known as MAO inhibitors, blood thinners, buprenorphine, butorphanol, carbamazepine, clarithromycin, fluconazole, itraconazole, ketoconazole, muscle relaxants, nefazadone, pentazocine, rifampin, ritonavir, sedatives, tranquilizers, or verapamil.

  • What are the possible side effects of Darvocet-N?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: drowsiness, dizziness, nausea, vomiting, constipation, abdominal pain, skin rashes, lightheadedness, headache, weakness, hallucinations, minor visual disturbances, and feelings of elation or discomfort.

    Liver dysfunction has been reported in association of both active components of Darvocet-N 50 and Darvocet-N 100.

  • Can I receive Darvocet-N if I am pregnant or breastfeeding?

    Darvocet-N should not be used during pregnancy unless your doctor knows you are pregnant and specifically recommends its use. Cases of temporary dependence in the newborn have occurred when the mother has taken propoxyphene consistently in the weeks before delivery. Low levels of propoxyphene have been detected in human breast milk.

  • What should I do if I miss a dose of Darvocet-N?

    If you miss a dose of the drug, skip that dose and resume your regular schedule. Do not take two doses at once.

  • How should I store Darvocet-N?

    Store at room temperature.

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I'm Kristen Dore, PharmD. Welcome to PDR Health!

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