Generic Name: Propoxyphene

  • What is Darvon-N?

    Darvon-N is a narcotic pain medication that is used for the relief of mild to moderate pain.

  • What is the most important information I should know about Darvon-N?

    Darvon-N is a potential drug of abuse. Do not share this medication with others.

    When taken in higher-than-recommended doses over long periods of time, Darvon-N can produce drug dependence. Take only as directed.

    There is a serious risk of overdose associated with Darvon-N, which may lead to death within the first hour of overdosing, especially in patients with a history of emotional disturbances or suicidal attempts or those who also take sedatives, tranquilizers, muscle relaxants, antidepressants, or other CNS depressants.

    Combining Darvon-N with certain medications or grapefruit juice may cause coma, respiratory depression or death. These drugs include some antiviral medications used to treat HIV (including ritonavir or atazanavir), antibiotics such as azithromycin or erythromycin, and antifungal medications such as fluconazole or ketoconazole.

    Darvon-N can make you sleepy, use care while driving a car or using machines until you know how this medication affects you.

  • Who should not take Darvon-N?

    Do not take Darvon-N if you have suicidal thoughts or have a history of addiction.

    Do not take Darvon-N if you are sensitive or allergic to propoxyphene.

    Do not take Darvon-N if you have a blockage of the bowel, or severe lung problems including decreased breathing capacity, asthma, or high amounts of carbon dioxide in the blood.

  • What should I tell my doctor before I take the first dose of Darvon-N?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Darvon-N. Make sure your doctor knows if you are taking tranquilizers, sleep aids, antidepressants, antihistamines, or any other drugs that make you sleepy. Also, talk to your doctor about your complete medical history, especially if you have ever had kidney or liver problems, problems with your pancreas or gallbladder, a head injury, if you use alcohol in excess, or if you have a history of addiction or suicidal thoughts.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: The usual dosage is 100 milligrams (mg) every 4 hours as needed for pain. Do not take more than six tablets in one day.

  • How should I take Darvon-N?

    Follow your doctor's directions exactly. Do not take more of the medication than your doctor prescribed.

    Do not stop taking Darvon-N abruptly if you have been taking it on a regular basis for a long time; you will need to lower the dose slowly to reduce the chance of withdrawal symptoms.

  • What should I avoid while taking Darvon-N?

    Avoid alcohol while taking this drug. The combination of alcohol with Darvon-N is dangerous and may lead to overdose symptoms such as weakness, difficulty in breathing, confusion, anxiety, and severe drowsiness and dizziness.

    Do not drink grapefruit juice while using Darvon-N.

  • What are possible food and drug interactions associated with Darvon-N?

    If Darvon-N is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Darvon-N with the following: alcohol, amiodarone, anticonvulsants, antidepressants (especially MAO inhibitors), blood thinners, buprenorphine, butorphanol, carbamazepine, clarithromycin, fluconazole, itraconazole, ketoconazole, muscle relaxants, nefazadone, pentazocine, rifampin, ritonavir, sedatives, tranquilizers, or verapamil.

  • What are the possible side effects of Darvon-N?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: abdominal pain, constipation, dizziness, drowsiness, feelings of elation or discomfort, hallucination, headache, lightheadedness, minor visual disturbances, nausea, skin rashes, vomiting, weakness

  • Can I receive Darvon-N if I am pregnant or breastfeeding?

    Do not take Darvon-N during pregnancy unless your doctor knows you are pregnant and specifically recommends its use. Cases of temporary dependence in newborns have occurred when the mother has taken drugs such as Darvon-N consistently in the weeks before delivery. Low levels of this drug have been detected in human breast milk. Discuss with your doctor whether it is safe to breastfeed while taking this drug.

  • What should I do if I miss a dose of Darvon-N?

    Take it as soon as you remember, but make sure the following doses are at least 4 hours apart. Do not take two doses at once.

  • How should I store Darvon-N?

    Store at room temperature.

Meet the Pharmacists

I'm Shereen A. Gharbia, PharmD. Welcome to PDR Health!

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