Generic Name: Methamphetamine

  • What is this medication and its most common uses?

    Desoxyn is a medicine used to treat attention-deficit hyperactivity disorder (ADHD). Desoxyn is also used for weight loss, along with a low calorie diet, in people who are overweight and have not been able to lose weight on other therapies.

    Desoxyn is a federally controlled substance because it has abuse potential.

  • What should I know when beginning and continuing on this medication?

    How does this medication work?

    Desoxyn works by changing the amount of certain chemicals in your brain, thereby improving symptoms of ADHD. Desoxyn also works by causing appetite suppression, leading to weight loss.

    What are the beneficial effects of this medication and when should I begin to have results?


    ADHD: Desoxyn is an important part of a total treatment program for people with ADHD that may include counseling or other therapies. Desoxyn may help increase attention and decrease impulsiveness and hyperactivity in people with ADHD.

    Weight Loss: Desoxyn has been shown to cause more weight loss when you take it along with dietary management compared to people on dietary management alone.


    ADHD: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you take Desoxyn exactly as your healthcare provider has prescribed.

    Weight Loss: Desoxyn may start working within the first weeks of therapy.

    How do I know it is working?

    You may start to notice improvement in your ADHD symptoms. You may also notice a reduction in your weight if you are using Desoxyn for weight loss. These are good indicators that your medication is working. Your healthcare provider may ask you questions from time to time to assess how well your medicine is working and to check for improvement of your condition.

  • What are the possible side effects of this medication?

    The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

    Desoxyn is a federally controlled substance because it can be abused or lead to dependence. Keep Desoxyn in a safe place to prevent misuse and abuse. Selling or giving away Desoxyn may harm others, and is against the law.

    More common side effects may include: fast heartbeat, tremors, dizziness, trouble sleeping, headache, weight loss, decreased appetite, dry mouth, stomach upset.

    Less common side effects may include:

    Sudden death in people who have heart problems or heart defects; stroke and heart attack in adults; increased blood pressure and heart rate with symptoms such as chest pain, shortness of breath, or fainting.

    Mental problems with symptoms such as new or worsening behavior and thought problems, bipolar illness, aggressive behavior, or hostility. Children and teenagers may also begin to hear voices, believe in things that are not true, or become suspicious.

    Slowing of growth (height and weight) in children.

    Seizures, mainly in people with a history of seizures.

    Eyesight changes or blurred vision.

  • Who should not take this medication?

    Do not take Desoxyn if you are allergic to it or any of its ingredients.

    Do not take Desoxyn if you are very anxious, tense, or agitated.

    Do not take Desoxyn if you have glaucoma (high pressure in the eye), tics (repeated movements or sounds that cannot be controlled), Tourette's syndrome (a brain disorder characterized by tics), or a family history of Tourette's syndrome.

    Do not take Desoxyn if you have high blood pressure, heart problems, or hyperthyroidism (an overactive thyroid gland).

    Do not take Desoxyn if you are taking an antidepressant medication called a monoamine oxidase inhibitor (MAOI) (such as phenelzine or selegiline) or have taken any within the past 14 days.

    Do not take Desoxyn if you have a history of drug abuse.

  • What should I tell my healthcare provider before I take the first dose of this medication?

    Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Desoxyn. Also, talk to your healthcare provider about your complete medical history, including heart problems, heart defects, high blood pressure, mental problems (such as psychosis, mania, bipolar disorder, or depression), or a family history of these problems; thyroid problems; tics or Tourette's syndrome; seizures; diabetes; or if you have ever abused or been dependent on alcohol, prescription medicines, or street drugs.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.


    Children >6 years: The recommended starting dose is 5 milligrams (mg) once or twice a day. Your healthcare provider may increase your dose as needed.

    Weight Loss

    Adults and children ≥12 years: The recommended starting dose is 5 mg half an hour before each meal.

  • How should I take this medication?

    Take Desoxyn exactly as prescribed by your healthcare provider. Do not change your dose or stop taking Desoxyn without first talking to your healthcare provider.

  • What should I avoid while taking this medication?

    Do not drive or operate machinery before you know how Desoxyn affects you.

  • What are the possible food and drug interactions associated with this medication?

    If Desoxyn is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Desoxyn with the following: antidepressants known as tricyclic antidepressants (such as amitriptyline or imipramine), phenothiazines (such as chlorpromazine or prochlorperazine), guanethidine, or insulin.

  • May I receive this medication if I am pregnant or breastfeeding?

    The effects of Desoxyn during pregnancy are unknown. Desoxyn can be found in your breast milk if you take it while breastfeeding. Do not breastfeed while you are taking Desoxyn. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of this medication?

    If you miss a dose of Desoxyn, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store this medication?

    Store at room temperature.

Meet the Pharmacists

I'm Shereen A. Gharbia, PharmD. Welcome to PDR Health!

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