Generic Name: Diethylpropion

  • What is this medication and its most common uses?

    Diethylpropion is a medicine used short-term (a few weeks), in combination with dieting, to help you lose weight. Diethylpropion is available as immediate-release tablets (a type of tablet that releases medicine into your body right away) and controlled-release tablets (a type of tablet that releases medicine into your body throughout the day).

    Diethylpropion is a federally controlled substance because it has abuse potential.

  • What should I know when beginning and continuing on this medication?

    How does this medication work?

    Diethylpropion works by decreasing your appetite.

    What are the beneficial effects of this medication and when should I begin to have results?

    What: When used as an add-on to dieting, diethylpropion may help you lose more weight than dieting alone.

    When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you take diethylpropion exactly as your healthcare provider has prescribed.

    How do I know it is working?

    You may start to notice a decrease in your weight. This is a good indicator that your medication is working. Your healthcare provider may ask you questions from time to time to assess how well your medicine is working, and may check your weight.

  • What are the possible side effects of this medication?

    The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

    More common side effects may include: increased blood pressure, nausea, vomiting, rash, changes in your sex drive, painful or excessive urination, hair loss, muscle pain, increased sweating.

    Less common side effects may include:

    Mental and physical dependence can occur. Keep diethylpropion in a safe place to prevent misuse and abuse.

    Pulmonary hypertension (a rare but serious disease of the lungs), with symptoms such as shortness of breath, unexplained chest pain, fainting, or swelling of your legs and feet.

    Seizures, mainly in people with a history of seizures.

  • Who should not take this medication?

    Do not take diethylpropion if you are allergic to it or any of its ingredients.

    Do not take diethylpropion if you have pulmonary hypertension, hardening of your arteries, hyperthyroidism (an overactive thyroid gland), glaucoma (increased pressure in the eye), or severe high blood pressure.

    Do not take diethylpropion if you are very anxious, tense, or agitated.

    Do not take diethylpropion if you have a history of drug abuse.

    Do not take diethylpropion in combination with other appetite suppressants (such as phentermine).

    Do not take diethylpropion if you are taking an antidepressant medication called a monoamine oxidase inhibitor (MAOI) (such as phenelzine or selegiline) or have taken any within the past 14 days.

  • What should I tell my healthcare provider before I take the first dose of this medication?

    Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with diethylpropion. Also, talk to your healthcare provider about your complete medical history, especially if you have heart problems (such as a heart murmur or an arrhythmia [a life-threatening irregular heartbeat]), high blood pressure, seizures, or if you plan to undergo surgery.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

    Immediate-Release Tablets

    Adults and adolescents >16 years: The usual dose is one 25-milligram (mg) tablet taken 3 times a day, 1 hour before meals. Your healthcare provider may tell you to take 1 tablet in the midevening to overcome night hunger.

    Controlled-Release Tablets

    Adults and adolescents >16 years: The usual dose is one 75-mg tablet taken once daily, in the midmorning.

  • How should I take this medication?

    Take diethylpropion exactly as prescribed by your healthcare provider. Do not change your dose or stop taking diethylpropion without first talking to your healthcare provider.

    If you are taking the controlled-release tablets, swallow them whole. Do not crush or chew the tablets.

  • What should I avoid while taking this medication?

    Do not drink alcohol or take medications that make you sleepy while taking diethylpropion.

    Do not drive, operate machinery, or engage in other dangerous activity until you know how diethylpropion affects you.

  • What are the possible food and drug interactions associated with this medication?

    If diethylpropion is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining diethylpropion with the following: blood pressure/heart medications (such as guanethidine or methyldopa), diabetes medicines (such as insulin), MAOIs, other appetite suppressants, or phenothiazines (such as chlorpromazine).

  • May I receive this medication if I am pregnant or breastfeeding?

    The effects of diethylpropion during pregnancy are unknown. Diethylpropion can be found in your breast milk if you take it while breastfeeding. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of this medication?

    If you miss a dose of diethylpropion immediate-release tablets, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

    If you miss a dose of diethylpropion controlled-release tablets, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store this medication?

    Store at room temperature.