Generic Name: Fidaxomicin

  • What is this medication and its most common uses?

    Dificid is a medicine used to treat diarrhea caused by Clostridium difficile, a type of bacteria that may cause severe or life-threatening diarrhea.

  • What should I know when beginning and continuing on this medication?

    How does this medication work?

    Dificid works by stopping the growth of Clostridium difficile, thereby treating your infection.

    What are the beneficial effects of this medication and when should I begin to have results?

    What: Dificid has been shown to improve diarrhea and other symptoms associated with Clostridium difficile.

    When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you take Dificid exactly as your healthcare provider has prescribed for the full course of treatment, even if your symptoms improve earlier.

    How do I know it is working?

    You may start to notice an improvement in your symptoms. This is a good indicator that your medication is working. Your healthcare provider may ask you questions and order tests to assess how well your infection is being treated.

  • What are the possible side effects of this medication?

    The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

    More common side effects may include: nausea, vomiting, abdominal (stomach area) pain, bleeding in your stomach or intestine, low red and white blood cell counts.

    Less common side effects may include:

    Serious allergic reactions, with symptoms such as rash; itching; difficulty breathing; or swelling of your face, lips, or tongue.

  • Who should not take this medication?

    Do not take Dificid if you are allergic to it or any of its ingredients.

  • What should I tell my healthcare provider before I take the first dose of this medication?

    Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Dificid. Also, talk to your healthcare provider about your complete medical history.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

    Adults: The recommended dose is 200 milligrams twice a day for 10 days.

  • How should I take this medication?

    Take Dificid exactly as prescribed by your healthcare provider. Do not change your dose or stop taking Dificid without first talking to your healthcare provider.

    Take Dificid with or without food.

  • What should I avoid while taking this medication?

    Do not skip doses. Skipping doses or not completing the full course of Dificid can decrease its effectiveness and can lead to the growth of bacteria that are resistant to the effects of Dificid.

  • What are the possible food and drug interactions associated with this medication?

    If Dificid is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Dificid with cyclosporine.

  • May I receive this medication if I am pregnant or breastfeeding?

    The effects of Dificid during pregnancy and breastfeeding are unknown. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of this medication?

    If you miss a dose of Dificid, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store this medication?

    Store at room temperature.