Generic Name: Fluconazole

  • What is Diflucan?

    Diflucan is used to treat vaginal yeast infections. Diflucan is also used for other conditions, including throat infections and fungal infections elsewhere in the body, such as infections of the urinary tract, peritonitis (inflammation of the abdomen lining), and pneumonia.

    Diflucan may also be prescribed to prevent fungal infections in certain patients as determined by your doctor.

  • What is the most important information I should know about Diflucan?

    Avoid Diflucan if you are allergic to any of its ingredients or to other medicines used to treat yeast and fungal infections.

    Strong allergic reactions to Diflucan, although rare, have been reported. Symptoms may include hives, itching, swelling, sudden drop in blood pressure, difficulty breathing or swallowing, diarrhea, or abdominal pain. If you experience any of these symptoms, notify your doctor immediately.

    Diflucan can cause liver damage in people with other medical conditions, especially AIDS or cancer and in people taking multiple medicines. Call your doctor right away if your skin or eyes become yellow, your urine is dark, your stools are pale, if you vomit or feel like vomiting, or if you have severe skin itching. Diflucan can also cause a severe rash with skin peeling in people with other medical conditions, especially AIDS or cancer.

    Diflucan capsules contain lactose and should not be given to people with lactose intolerance or problems absorbing sugar (such as glucose/galactose malabsorption, galactose intolerance, Lapp lactase deficiency). Diflucan oral suspension contains sucrose (sugar) and should not be used in people with problems absorbing sugar.

  • Who should not take Diflucan?

    Do not take Diflucan if you are allergic to any of its ingredients or have ever had an allergic reaction to similar drugs, such as ketoconazole. Make sure your doctor is aware of any drug reactions you have experienced.

    To avoid a possible serious reaction, do NOT take Diflucan if you are taking erythromycin, astemizole, pimozide, quinidine, and cisapride. Also, do not take Diflucan with a drug called terfenadine if you are taking more than 400 milligrams (mg) of Diflucan.

  • What should I tell my doctor before I take the first dose of Diflucan?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Diflucan. Also, talk to your doctor about your complete medical history, especially if you have liver problems, any other medical conditions, are allergic to any other medicines, including those used to treat yeast and other fungal infections, have a compromised immune system (such as AIDS or cancer), heart problems such as irregular heartbeats caused or worsened by medicines, kidney problems or are on dialysis, lactose intolerance or problems absorbing sugar, are pregnant, plan to become pregnant, think you might be pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    The dosage your doctor prescribes will depend on the type of infection you have as well as your body's response to the drug. Your doctor may adjust your dose if you have kidney problems or are on dialysis.

    Vaginal Infections

    Adults: The recommended dose of Diflucan is 150 mg as a single oral dose.

    Oral and Esophageal Infections

    Adults: The recommended dose of Diflucan is 200 mg on the first day, followed by 100 mg once daily. Based on the type of your infection, your doctor will let you know the duration of your treatment.

    Children: Your doctor will prescribe the appropriate dose for your child based on their body weight and type of infection.

  • How should I take Diflucan?

    Take Diflucan by mouth with or without food. You can take Diflucan at any time of the day. If there is no change in your symptoms after a few days, call your doctor. If you are taking the oral suspension, shake well before using.

    Take this medication exactly as prescribed, and continue taking it for as long as your doctor instructs. You may begin to feel better after the first few days; however, it takes weeks or even months of treatment to completely cure certain fungal infections.

  • What should I avoid while taking Diflucan?

    Some medications can affect how well Diflucan works. Check with your doctor before starting any new medicines within 7 days of taking Diflucan.

    Avoid stopping therapy before it is recommended by your doctor, even if you start to feel better. Avoid driving or operating machinery until you know how Diflucan affects you.

  • What are possible food and drug interactions associated with Diflucan?

    If Diflucan is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Diflucan with the following: afentanil; antiviral medications used to treat AIDS; amitriptyline; amphotericin B; astemizole; blood pressure medicines such as hydrochlorothiazide, losartan, amlodipine, nifedipine, or felodipine; blood thinners; carbamazepine; cholesterol-lowering drugs such as atorvastatin, simvastatin, and fluvastatin; cisapride; cyclosporine, tacrolimus or sirolimus (used to prevent rejection of organ transplants); cyclophosphamide; diabetes medicines; erythromycin; fentanyl; halofantrine; quinidine; methadone; nonsteroidal anti-inflammatory drugs (NSAIDs) including celecoxib, ibuprofen, and naproxen; nortriptyline; phenytoin; pimozide; prednisone; rifabutin; rifampin; triazolam; terfenadine; theophylline; vitamin A; vincristine; or vinblastine.

    Do not take >400 mg of Diflucan with terfenadine due to increased drug-drug interactions.

  • What are the possible side effects of Diflucan?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: allergic reactions, liver damage, irregular heart rhythm, severe rash with skin peeling, stomach pain, nausea or upset stomach, headache, diarrhea, dizziness, changes in the way food tastes

  • Can I receive Diflucan if I am pregnant or breastfeeding?

    The effects of Diflucan during pregnancy are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, are breastfeeding, or plan to breastfeed. Diflucan is not recommended if you are breastfeeding.

  • What should I do if I miss a dose of Diflucan?

    If you miss a dose of Diflucan, take the missed dose as soon as you remember it. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store Diflucan?

    Store at room temperature. Do not freeze Diflucan oral suspension. Discard unused amounts of Diflucan oral suspension after 2 weeks.

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