Generic Name: Chlorothiazide

  • What is Diuril?

    Diuril is a diuretic (water pill) used to treat high blood pressure and other conditions that require the elimination of excess water from the body. These conditions include congestive heart failure, cirrhosis (scarring of the liver), corticosteroid and estrogen therapy, and kidney disease. When used for high blood pressure, Diuril can be used alone or with other blood pressure medications.

  • What is the most important information I should know about Diuril?

    Diuril may cause an imbalance of fluid or electrolytes, such as sodium and potassium, in the body. Signs or symptoms of imbalance include dry mouth, thirst, weakness, drowsiness, confusion, muscle pains or cramps, and nausea and vomiting. Notify your doctor immediately if you experience such signs or symptoms.

    Diuril may cause dizziness, lightheadedness, or fainting; alcohol may increase these effects. Diuril may increase your blood sugar.

  • Who should not take Diuril?

    If you are unable to urinate, you should not take this medication. If you are sensitive to or have ever had an allergic reaction to Diuril or other similar diuretics, or if you are sensitive to sulfonamide drugs, you should not take this medication.

  • What should I tell my doctor before I take the first dose of Diuril?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with this drug. Also, talk to your doctor about your complete medical history, especially if you have kidney or liver problems, diabetes, gout (a complex form of arthritis characterized by sudden, severe attacks of pain and redness in the joints), lupus (a disease that affects the immune system), bronchial asthma, or a history of allergies.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Fluid Retention

    Adults: The usual dose is 500 milligrams (mg) to 1,000 mg once or twice a day. Some patients may have Diuril administered on alternate days or 3-5 days each week.

    Infants and children: Your doctor will prescribe the appropriate dose for your child based on their body weight.

    High Blood Pressure

    Adults: The usual starting dose is 500 mg or 1,000 mg a day as a single or divided dose. Rarely, some patients may require up to 2,000 mg a day in divided doses.

    Infants and children: Your doctor will prescribe the appropriate dose for your child based on their body weight.

  • How should I take Diuril?

    Take Diuril exactly as your doctor prescribes it.

  • What should I avoid while taking Diuril?

    Avoid becoming overheated, and be careful when exercising and in hot weather. Dehydration, excessive sweating, severe diarrhea, or vomiting could deplete your body's fluids and lower your blood pressure too much.

    Alcohol may increase the chance of dizziness occurring. Avoid alcohol while taking this medication.

  • What are possible food and drug interactions associated with Diuril?

    If Diuril is taken with certain other drugs, the effects of either may be increased, decreased, or altered. It is especially important to check with your doctor before combining Diuril with the following: alcohol, barbiturates such as phenobarbital and secobarbital, cholesterol-lowering drugs such as cholestyramine and colestipol, drugs to treat diabetes such as insulin and glyburide, lithium, muscle relaxants such as tubocurarine, narcotic painkillers such as oxycodone, nonsteroidal anti-inflammatory drugs such as ibuprofen and naproxen, norepinephrine, other drugs for high blood pressure such as captopril and nifedipine, and steroids such as prednisone.

  • What are the possible side effects of Diuril?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: abdominal cramps, allergic reactions, anemia, changes in blood sugar, constipation, diarrhea, difficulty breathing, dizziness, dizziness on standing up, fever, fluid in lungs, fluid and electrolyte imbalance, muscle spasms, nausea, rash, sensitivity to light, stomach upset, blurred vision, vomiting, weakness, yellowing of the skin and eyes

  • Can I receive Diuril if I am pregnant or breastfeeding?

    The effects of Diuril during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Diuril?

    If you miss a dose of Diuril, take the missed dose as soon as you remember it. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store Diuril?

    Store at room temperature.

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