Generic Name: Doxepin

  • What is Doxepin?

    Doxepin is a medication used to treat depression and anxiety.

  • What is the most important information I should know about Doxepin?

    Antidepressant medicines, like doxepin, may increase suicidal thoughts or actions in some children, teenagers, and young adults when the medicine is first started.

    Pay close attention to any sudden changes in mood, behaviors, thoughts, or feelings. This is very important when an antidepressant medicine is first started or when the dose is changed.

    Call your doctor immediately if you feel new or worsening depression/anxiety, agitation, insomnia, hostility, panic attacks, restlessness, extreme hyperactivity, or suicidal thinking or behavior.

    Keep all follow-up visits as scheduled, and call your doctor between visits as needed, especially if you have concerns about symptoms.

  • Who should not take Doxepin?

    Do not take doxepin if you have ever had an allergic reaction or sensitivity to it or any of its ingredients.

    Do not take doxepin if you have glaucoma (high pressure in the eyes) or difficulty urinating.

  • What should I tell my doctor before I take the first dose of Doxepin?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with doxepin. Also, talk to your doctor about your complete medical history, especially if you have glaucoma or difficulty urinating.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: The starting dose is 75 milligrams (mg) a day. Your doctor may increase your dose as appropriate.

  • How should I take Doxepin?

    Take doxepin exactly as prescribed. It may take several weeks for you to feel better.

  • What should I avoid while taking Doxepin?

    Doxepin may cause you to become drowsy or less alert; do not drive, operate dangerous machinery, or participate in any hazardous activity that requires full mental alertness until you know how this medication affects you.

    Do not drink alcohol while you are taking doxepin. Alcohol increases the danger of an overdose.

  • What are possible food and drug interactions associated with Doxepin?

    If doxepin is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining doxepin with the following: alcohol, antidepressants, including certain antidepressant medications in a class called monoamine oxidase inhibitors (MAOIs), such as phenelzine and tranylcypromine, carbamazepine, cimetidine, clonidine, flecainide, guanethidine, propafenone, quinidine, and tolazamide.

  • What are the possible side effects of Doxepin?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: blurred vision, constipation, diarrhea, dizziness, drowsiness, dry mouth, itchy or scaly skin (pruritus), light sensitivity, loss of appetite, low blood pressure, nausea, rapid or irregular heartbeat, rash, trouble urinating, vomiting, water retention, weight changes

  • Can I receive Doxepin if I am pregnant or breastfeeding?

    The effects of doxepin during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Doxepin?

    If you miss a dose of doxepin, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store Doxepin?

    Store at room temperature.