Generic Name: Pioglitazone hydrochloride and glimepiride

  • What is Duetact?

    Duetact is used, with diet and exercise, to help stabilize the blood sugar levels in people with type 2 diabetes who fail to control their sugar levels with other forms of therapy.
  • What is the most important information I should know about Duetact?

    Drugs for low blood sugar should not be taken with Duetact; this can result in severe cardiovascular problems that may result in death.
  • Who should not take Duetact?

    Do not take Duetact if you are allergic to any of its ingredients, or if you have diabetic ketoacidosis. This problem should be treated with insulin.
  • What should I tell my doctor before I take the first dose of Duetact?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking to avoid an interaction with Duetact. Also, talk to your doctor about your complete medical history, especially about all of the forms of type 2 diabetic treatment you have taken.
  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Starting dose for people currently taking glimepiride alone: Based on the usual starting dose of pioglitazone (15 milligrams [mg] or 30 mg daily), Duetact may be taken as either a 30 mg/2 mg or 30 mg/4 mg tablet once daily.

    Starting dose for people currently taking pioglitazone alone: Based on the usual starting dose of glimepiride (1 mg or 2 mg once daily), and pioglitazone 15 mg or 30 mg, Duetact may be taken as a 30 mg/2 mg tablet, once daily.

  • How should I take Duetact?

    Duetact should be taken once a day with the first main meal of the day.
  • What should I avoid while taking Duetact?

    Avoid getting pregnant while on Duetact. Talk to your doctor if you plan to become pregnant while on this type 2 diabetes therapy.
  • What are the possible side effects of Duetact?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: diarrhea, headache, lower blood sugar, nausea, pain in legs, upper respiratory tract infection, urinary tract infection, weight gain

  • Can I receive Duetact if I am pregnant or breastfeeding?

    Talk to your doctor if you are pregnant, planning to become pregnant, or nursing. Duetact is not recommended for pregnant women; blood sugar level should be maintained with insulin during pregnancy. Also, Duetact may pass into breast milk.
  • How should I store Duetact?

    Store at room temperature, away from dampness.