What is DuoNeb?DuoNeb is a combination of two medicines that work together to help open the airways in your lungs. It is used to help treat airway narrowing (bronchospasm) that happens with chronic obstructive pulmonary disease (COPD) in adult patients requiring more than one bronchodilator medicine.
What is the most important information I should know about DuoNeb?DuoNeb is to be used with a nebulizer. You should use DuoNeb in an appropriate way to achieve its full potential.
Do not exceed the recommended dose or frequency of DuoNeb without consulting with your doctor.
Who should not take DuoNeb?Do not take DuoNeb if you are allergic to any ingredient in it or to atropine.
DuoNeb has not been studied in patients <18 years of age.
What should I tell my doctor before I take the first dose of DuoNeb?Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with DuoNeb. Also, talk to your doctor about your complete medical history, especially if you are pregnant or plan to become pregnant, have high blood pressure or heart problems, have diabetes, have or have had seizures, have a thyroid problem called hyperthyroidism, have an eye problem called narrow-angle glaucoma, have liver or kidney problems, or have problems urinating due to bladder-neck blockage or an enlarged prostate (men).
What is the usual dosage?The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.
Adults: The usual dose is one 3 milliliter (mL) vial administered four times daily via a nebulizer. An increase of two 3 mL doses may be added after consulting with your doctor.
How should I take DuoNeb?Take the appropriate dose (3 mL) every 6 hours. DuoNeb needs to be administered via a jet nebulizer that is connected to an air compressor with adequate air flow, equipped with a face mask. Use as directed by your doctor.
DuoNeb may help to open your airways for up to 5 hours after taking this medicine. If DuoNeb does not help your airway narrowing (bronchospasm) or your bronchospasm gets worse, call your doctor right away or get emergency help if needed.
To use DuoNeb, remove one vial from the foil pouch. Twist the cap completely off the vial and squeeze the contents into the nebulizer reservoir. Connect the nebulizer to the mouthpiece or face mask. Connect the nebulizer to the compressor, then sit in a comfortable, upright position and turn it on. Breathe as calmly, deeply, and evenly as possible through your mouth until no more mist is formed. Clean the nebulizer according to the manufacturer's instructions.
What should I avoid while taking DuoNeb?Avoid spraying DuoNeb into your eyes while using your nebulizer as it may lead to enlarged pupils, blurry vision, or eye pain. In addition, do not use more than required without consulting with your doctor.
What are possible food and drug interactions associated with DuoNeb?If DuoNeb is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining DuoNeb with the following: anticholinergic agents (such as ipratropium bromide), including Parkinson's disease medicines; beta-adrenergic agents (sympathomimetics such as albuterol sulfate); beta-receptor blocking agents; diuretics; monoamine oxidase inhibitors; and tricyclic antidepressants.
What are the possible side effects of DuoNeb?Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.
Side effects may include: blurry vision, bronchitis, change in voice, chest pain, cough, diarrhea, headache, hives, indigestion, leg cramps, lung disease, nausea, rash, swelling of the face/eyelids/lips, upper respiratory infection, urinary tract infection
Can I receive DuoNeb if I am pregnant or breastfeeding?The effects of DuoNeb during pregnancy and breastfeeding are unknown. Talk to your doctor if you are pregnant, plan to become pregnant, or are breastfeeding.
What should I do if I miss a dose of DuoNeb?If you miss a dose, take it as soon as you remember. If it is close to the time of your next dose, skip it and resume your scheduled dose. Do not take two doses at once.
How should I store DuoNeb?Store at room temperature. Keep the vials in the foil pouch to protect from light.
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