Generic Name: Rilpivirine

  • What is Edurant?

    Edurant is a medicine used to treat HIV (human immunodeficiency virus) infection (AIDS) in combination with other anti-HIV medications. Edurant is a type of HIV medicine called a non-nucleoside reverse transcriptase inhibitor (NNRTI). Edurant is used in adults who have never taken HIV medicines before.

  • What is the most important information I should know about Edurant?

    You have to take Edurant with other HIV medicines.

    Always stay on continuous HIV therapy to control your HIV infection and decrease HIV-related illnesses. Though Edurant can slow the progress of HIV, it is not a cure. You may continue to develop infections and other complications associated with HIV.

    Always practice safe sex to reduce the risk of transmitting HIV to others. Use latex or polyurethane condoms to lower the chance of sexual contact with any body fluids, such as semen, vaginal secretions, or blood.

    Edurant can cause depression or mood changes. Tell your doctor immediately if you have feelings of sadness or hopelessness, if you are feeling anxious or restless, or if you have thoughts of hurting yourself (suicide) or have tried to hurt yourself.

    Edurant can cause changes in your body fat. These changes may include an increased amount of fat in your upper back and neck ("buffalo hump"), breast, and around the middle of your body. Loss of fat from your legs, arms, and face may also occur.

    Changes in your immune system can occur when you start taking Edurant. Your immune system may get stronger and begin to fight infections that have been hidden in your body for a long time. Call your doctor immediately if you start having new symptoms after starting Edurant.

  • Who should not take Edurant?

    Do not take Edurant if you are allergic to it or any of its ingredients.

    Do not take Edurant if you have been previously treated with anti-HIV medications.

    Do not take Edurant if you are currently taking carbamazepine, dexamethasone (if you are taking more than one dose), oxcarbazepine, phenobarbital, phenytoin, proton pump inhibitors (such as esomeprazole, lansoprazole, omeprazole, pantoprazole, or rabeprazole), rifabutin, rifampin, rifapentine, or if you are taking St. John's wort.

  • What should I tell my doctor before I take the first dose of Edurant?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Edurant. Also, talk to your doctor about your complete medical history, especially if you have had or currently have liver problems, including hepatitis B or C, have ever had a mental health problem, are pregnant, plan to become pregnant, or if you are breastfeeding or plan to breastfeed.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: The recommended dose is one 25-milligram (mg) tablet taken once a day with a meal.

  • How should I take Edurant?

    Take Edurant every day exactly as prescribed by your doctor. Do not change your dose or stop taking Edurant without first talking with your doctor. You have to see your doctor regularly while taking Edurant.

    Always take Edurant with a meal. Taking Edurant with a meal is important to help get the right amount of medicine in your body. Keep in mind that a protein drink alone does not replace a meal.

    When your supply of Edurant starts to run low, get more from your doctor or pharmacy. It is important that you do not run out of Edurant. The amount of HIV in your blood may increase if the medicine is stopped even for a short time.

  • What should I avoid while taking Edurant?

    Do not breastfeed while you are taking Edurant.

    Avoid high-risk activities such as unprotected sex and the sharing of needles. Edurant does not cure HIV or AIDS. You can still transmit the virus to others during therapy with this medication.

  • What are possible food and drug interactions associated with Edurant?

    If Edurant is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Edurant may interact with numerous medications. Therefore, it is very important that you tell your doctor about any other medications you are taking.

  • What are the possible side effects of Edurant?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: headache, rash, trouble sleeping

  • Can I receive Edurant if I am pregnant or breastfeeding?

    The effects of Edurant during pregnancy and breastfeeding are unknown. It is recommended that you do not breastfeed your baby if you are infected with HIV. This is because your baby could become infected with HIV through your breast milk. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Edurant?

    If you miss a dose of Edurant within 12 hours of the time you usually take it, take your dose of Edurant with a meal as soon as possible. Then, take your next dose of Edurant at the regularly scheduled time. If you miss a dose of Edurant by more than 12 hours of the time you usually take it, wait, and then take the next dose of Edurant at the regularly scheduled time. Do not take more than your prescribed dose to make up for a missed dose.

  • How should I store Edurant?

    Store at room temperature and keep it in the original bottle to protect from light.