Generic Name: Prasugrel

  • What is this medication and its most common uses?

    Effient is a medicine used to treat people who have had a heart attack or severe chest pain due to heart problems, and those who have been treated with a procedure called angioplasty.

  • What should I know when beginning and continuing on this medication?

    How does this medication work?

    Blood clots form when certain blood cells, called platelets, clump together. Effient works by making platelets in the blood less sticky, so they are less likely to clump together and form blood clots.

    What are the beneficial effects of this medication and when should I begin to have results?

    What: Effient helps lower your chance of having another serious problem with your heart or blood vessels, such as another heart attack, a stroke, or blood clots in your stent.

    When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you take Effient exactly as your healthcare provider has prescribed.

    How do I know it is working?

    Your healthcare provider will monitor you regularly to check how well this medication is working.

  • What are the possible side effects of this medication?

    The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

    Effient can cause bleeding that can be serious and sometimes life-threatening. You may have a higher risk of bleeding if you take Effient and weigh less than 132 pounds; have stomach or intestinal bleeding that is recent or keeps coming back; a stomach ulcer, liver or kidney problems, or trauma (such as an accident or surgery); or also take other medicines that increase your risk of bleeding (such as heparin, nonsteroidal anti-inflammatory drugs [NSAIDs] [such as ibuprofen or naproxen], warfarin, or other medicines to prevent or treat blood clots).

    Call your healthcare provider right away if you experience unusual bruising (bruises that develop without known cause or grow in size), nosebleeds, bleeding from cuts that takes a long time to stop, pink or brown urine, red or black stools, coughing up blood, or vomiting blood or material that looks like coffee grounds.

    More common side effects may include: bleeding.

    Less common side effects may include:

    Thrombotic thrombocytopenic purpura (a condition in which blood clots form in the blood vessels and can occur all over the body), with symptoms such as purplish spots on your skin or in your mouth, paleness or yellowing of your skin or the whites of your eyes, tiredness, weakness, fever, fast heartbeat, shortness of breath, headache, speech changes, confusion, stroke, seizure, low amount of urine or urine that is pink or has blood in it, abdominal (stomach area) pain, nausea, vomiting, diarrhea, or vision changes.

    Serious allergic reactions, with symptoms such as hives; swelling of your face, lips, throat, or in or around your mouth; trouble breathing or swallowing; chest pain or pressure; or dizziness or fainting.

  • Who should not take this medication?

    Do not take Effient if you are allergic to it or any of its ingredients.

    Do not take Effient if you currently have abnormal bleeding (such as stomach or intestinal bleeding, or bleeding in your head).

    Do not take Effient if you have had a stroke or "mini-stroke."

  • What should I tell my healthcare provider before I take the first dose of this medication?

    Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Effient. Also, talk to your healthcare provider about your complete medical history, especially if you have bleeding, liver, or kidney problems; a history of stomach ulcers, colon polyps (non-cancerous growths on the surface of the colon), diverticulosis (a condition in which pockets form in the large intestine), or stroke or "mini-stroke"; any recent severe injury or surgery; are planning to have surgery (such as a heart bypass) or a dental procedure; or if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

    Adults: The recommended dose is 10 milligrams (mg) once a day. Your healthcare provider will give you a single 60-mg dose before having you take 10 mg a day.

    If you are underweight, your healthcare provider may adjust your dose appropriately.

    It is important that you do not stop taking this medication abruptly. If you need to change or stop taking this medication, it is important that you only do this with the guidance of your healthcare provider.

  • How should I take this medication?

    Take Effient exactly as prescribed by your healthcare provider. Do not change your dose or stop taking Effient without first talking to your healthcare provider.

    Take Effient with or without food.

    Take Effient with aspirin as instructed by your healthcare provider.

  • What should I avoid while taking this medication?

    Do not stop taking Effient without first talking to your healthcare provider. Stopping Effient earlier than recommended may increase your risk of heart problems.

  • What are the possible food and drug interactions associated with this medication?

    If Effient is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Effient with the following: NSAIDs or warfarin.

  • May I receive this medication if I am pregnant or breastfeeding?

    The effects of Effient during pregnancy and breastfeeding are unknown. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of this medication?

    If you miss a dose of Effient, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule.

  • How should I store this medication?

    Store at room temperature.

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