Generic Name: Asparaginase Erwinia chrysanthemi

  • What is Erwinaze?

    Erwinaze is a medicine used to treat acute lymphoblastic leukemia (ALL) in people who have developed an allergy to Escherichia coli-derived asparaginase and pegaspargase. Erwinaze is administered intramuscularly (injected into the muscle).

  • What is the most important information I should know about Erwinaze?

    A serious allergic reaction that may result in death if not immediately treated can occur while using Erwinaze. Tell your doctor immediately if you develop a rash or breathing problems.

    Erwinaze can cause pancreatitis (inflammation of the pancreas). Tell your doctor immediately if you experience abdominal pain.

    Erwinaze can cause abnormally high blood sugar levels. Your doctor will monitor your blood sugar levels before you start Erwinaze and during treatment.

    Blood clots or abnormal bleeding events can occur while using Erwinaze. Tell your doctor immediately if you experience headache, arm or leg swelling, shortness of breath, or chest pain.

  • Who should not take Erwinaze?

    Your doctor will not administer Erwinaze to you if you are allergic to it, any of its ingredients, or if you have a history of serious pancreatitis, blood clots, or bleeding events with prior asparaginase treatment.

  • What should I tell my doctor before I take the first dose of Erwinaze?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Erwinaze. Also, talk to your doctor about your complete medical history, especially if you have pancreatitis, have blood clots or bleeding disorders, have high blood sugar, are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults and children: Your doctor will administer the appropriate dose for you based on your weight and previous pegaspargase or native E. coli asparaginase treatment.

  • How should I take Erwinaze?

    Your doctor will administer Erwinaze to you.

  • What should I avoid while taking Erwinaze?

    Do not miss your scheduled follow-up appointments with your doctor.

  • What are possible food and drug interactions associated with Erwinaze?

    No significant interactions have been reported with Erwinaze at this time. However, always tell your doctor about any medicines you take, including over-the-counter medications, vitamins, and herbal supplements.

  • What are the possible side effects of Erwinaze?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: allergic reactions (maybe serious), bleeding, blood clotting abnormalities, high blood sugar, liver problems, nausea, pancreatitis, vomiting

  • Can I receive Erwinaze if I am pregnant or breastfeeding?

    The effects of Erwinaze during pregnancy are unknown. Your doctor will not administer Erwinaze while you are breastfeeding. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Erwinaze?

    Erwinaze should be given under special circumstances determined by your doctor.

  • How should I store Erwinaze?

    Your doctor will store this medication for you.